Powder: -20°C for 3 years | In solvent: -80°C for 1 year
Lotilaner is a parasiticide. It is used as a potent non-competitive antagonist of insects GABACl receptors (IC50 of 23.84 nM for Drosophila melanogaster GABA receptor). It also has no effect on a dog GABAA receptor.
説明 | Lotilaner is a parasiticide. It is used as a potent non-competitive antagonist of insects GABACl receptors (IC50 of 23.84 nM for Drosophila melanogaster GABA receptor). It also has no effect on a dog GABAA receptor. |
ターゲット&IC50 | GABA:23.84 nM(DmS), GABA:36.79 nM(Rm), GABA:38.25 nM(DmR2), GABA:52.40 nM(Ls-GABA1) |
In vitro | Lotilaner displays IC50s of 38.25 ± 3.75, 52.40 ± 4.54, 36.79 ± 4.39 nM for Drosophila melanogaster dieldrin/fipronil-resistant forms (DmR2), Lepeophtheirus salmonis (Ls) and Rhipicephalus microplus (Rm) GABACl receptors, respectively. |
分子量 | 596.76 |
分子式 | C20H14Cl3F6N3O3S |
CAS No. | 1369852-71-0 |
Powder: -20°C for 3 years | In solvent: -80°C for 1 year
DMSO: ≥ 150 mg/mL (251.36 mM)
You can also refer to dose conversion for different animals. 詳細
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Lotilaner 1369852-71-0 Membrane transporter/Ion channel Microbiology/Virology Neuroscience GABA Receptor Parasite Inhibitor γ-Aminobutyric acid Receptor inhibit Gamma-aminobutyric acid Receptor inhibitor