Powder: -20°C for 3 years | In solvent: -80°C for 1 year
ML116 is a potent and selective STAT3 inhibitor.
説明 | ML116 is a potent and selective STAT3 inhibitor. |
In vitro | Probe ML116 exhibits a STAT3 IC50 value of approximately 4 micromolar and does not inhibit the STAT1, STAT5, or NFkB signaling pathways (IC50 values greater than 56 micromolar), as determined using cell-based luciferase reporter assays.?Quantitative PCR experiments demonstrated that probe ML116 inhibits transcription of the STAT3-regulated gene BCL3 |
分子量 | 309.43 |
分子式 | C18H19N3S |
CAS No. | 744270-00-6 |
Powder: -20°C for 3 years | In solvent: -80°C for 1 year
DMSO: 3.1 mg/mL (10 mM)
You can also refer to dose conversion for different animals. 詳細
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ML116 744270-00-6 JAK/STAT signaling Stem Cells STAT ML 116 ML-116 Inhibitor inhibitor inhibit