Powder: -20°C for 3 years | In solvent: -80°C for 1 year
ML251 is a potent novel nanomolar inhibitor of T. brucei and T. cruzi phosphofructokinase[1]. ML251 inhibits T. brucei PFK (IC50=0.37 μM) and T. cruzi PFK (IC50=0.13 μM). ML251 can be used for the research of parasite[1].
説明 | ML251 is a potent novel nanomolar inhibitor of T. brucei and T. cruzi phosphofructokinase[1]. ML251 inhibits T. brucei PFK (IC50=0.37 μM) and T. cruzi PFK (IC50=0.13 μM). ML251 can be used for the research of parasite[1]. |
ターゲット&IC50 | PFK (T. b. brucei):0.37 μM, PFK (T. cruzi):0.13 μM |
In vitro | ML251 produces modest dose-dependent toxicity[1]. |
細胞研究 | The cell cytotoxicity assay of ML251 (0~33.3 μg/mL) in T. brucei cell shows dose-dependent reduction of cell viability[1]. |
分子量 | 426.27 |
分子式 | C17H13Cl2N3O4S |
CAS No. | 1486482-16-9 |
Powder: -20°C for 3 years | In solvent: -80°C for 1 year
DMSO: 50 mg/mL (117.3 mM), Sonication is recommended.
You can also refer to dose conversion for different animals. 詳細
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ML251 1486482-16-9 Metabolism Microbiology/Virology Glucokinase Parasite cruzi inhibit ML 251 brucei MRC-5 Inhibitor nanomolar ML-251 inhibitor