Powder: -20°C for 3 years | In solvent: -80°C for 1 year
MS-PPOH is a potent and selective inhibitor of cytochrome P450 (CYP) epoxygenase. MS-PPOH inhibits CYP2C8 and CYP2C9 with IC50s of 15 and 11 µM, respectively
パッケージサイズ | 在庫状況 | 単価(税別) | |||
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1 mg | 在庫あり | ¥ 8,000 | |||
5 mg | 在庫あり | ¥ 18,500 | |||
10 mg | 在庫あり | ¥ 33,000 | |||
25 mg | 在庫あり | ¥ 61,000 | |||
50 mg | 在庫あり | ¥ 91,500 | |||
100 mg | 在庫あり | ¥ 137,000 | |||
1 mL * 10 mM (in DMSO) | 在庫あり | ¥ 20,500 |
説明 | MS-PPOH is a potent and selective inhibitor of cytochrome P450 (CYP) epoxygenase. MS-PPOH inhibits CYP2C8 and CYP2C9 with IC50s of 15 and 11 µM, respectively |
In vitro | MS-PPOH blocks cellular EET synthesis. MS-PPOH inhibits tonic (basal) cell invasion and migration and reduces the 11,12-EET (1.0 μM)-induced cell motility[1]. |
In vivo | MS-PPOH (20 mg/kg/day, i.v.) for 6 days significantly reduced renal levels of epoxyeicosatrienoic acids (EETs) in Dahl salt-resistant rats on 2% NaCl drinking solution[3]. |
分子量 | 323.41 |
分子式 | C16H21NO4S |
CAS No. | 206052-02-0 |
Powder: -20°C for 3 years | In solvent: -80°C for 1 year
DMSO: 27mg/mL (83.5mM)
You can also refer to dose conversion for different animals. 詳細
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MS-PPOH 206052-02-0 Metabolism P450 MS PPOH MSPPOH Inhibitor inhibitor inhibit