Powder: -20°C for 3 years | In solvent: -80°C for 1 year
N-Acetyl lysyltyrosylcysteine amide acetate is an effective and selective tripeptide inhibitor of myeloperoxidase (MPO). N-Acetyl lysyltyrosylcysteine amide acetate inhibits MPO-dependent hypochlorous acid (HOCl) generation, protein nitration, and LDL ox
パッケージサイズ | 在庫状況 | 単価(税別) |
---|---|---|
1 mg | お問い合わせ | ¥ 20,000 |
5 mg | お問い合わせ | ¥ 45,500 |
10 mg | お問い合わせ | ¥ 80,000 |
25 mg | お問い合わせ | ¥ 143,500 |
50 mg | お問い合わせ | ¥ 215,000 |
100 mg | お問い合わせ | ¥ 321,000 |
200 mg | お問い合わせ | ¥ 485,000 |
説明 | N-Acetyl lysyltyrosylcysteine amide acetate is an effective and selective tripeptide inhibitor of myeloperoxidase (MPO). N-Acetyl lysyltyrosylcysteine amide acetate inhibits MPO-dependent hypochlorous acid (HOCl) generation, protein nitration, and LDL ox |
In vivo | N-Acetyl lysyltyrosylcysteine amide acetate (10 mg/kg; i.p.; daily 7 days) significantly protects BBB function and decreased neutrophil infiltration. N-Acetyl lysyltyrosylcysteine amide acetate (10 mg/kg; i.p.; daily 7 days) significantly reduces microglia/macrophage activation and neuron loss in MCAO mice. N-Acetyl lysyltyrosylcysteine amide acetate (10 mg/kg; i.p.; daily for 3-7 days) decreases apoptosis and cell injury in the brains of MCAO mice. N-Acetyl lysyltyrosylcysteine amide acetate reduced MPO in the brains of MCAO mice. N-Acetyl lysyltyrosylcysteine amide acetate reduces NO2Tyr and 4-HNE in MCAO mice. N-Acetyl lysyltyrosylcysteine amide acetate significantly decreases infarct size, blood-brain barrier leakage, infiltration of myeloid cells, loss of neurons, and apoptosis in the brains of middle cerebral artery occlusion (MCAO) mice. N-Acetyl lysyltyrosylcysteine amide acetate (10 mg/kg; i.p.; daily for 3-7 days) significantly reduces neurological severity scores and infarct size in MCAO mice[2]. |
別名 | N-Acetyl lysyltyrosylcysteine amide acetate(1287585-40-3 Free base) |
分子量 | 513.61 |
分子式 | C22H35N5O7S |
Powder: -20°C for 3 years | In solvent: -80°C for 1 year
You can also refer to dose conversion for different animals. 詳細
bottom
Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc.
N-Acetyl lysyltyrosylcysteine amide acetate Metabolism Glutathione Peroxidase N-Acetyl lysyltyrosylcysteine amide acetate(1287585-40-3 Free base) NAcetyl lysyltyrosylcysteine amide acetate N-Acetyl lysyltyrosylcysteine amide Acetate N Acetyl lysyltyrosylcysteine amide acetate Inhibitor inhibitor inhibit