keep away from moisture
Powder: -20°C for 3 years | In solvent: -80°C for 1 year
Nemifitide acetate(173240-15-8 free base) (INN 00835 acetate) is a synthetic pentapeptide antidepressant with a potential for rapid onset of action. It is a peptide analog of melanocyte-inhibiting factor (MIF).
パッケージサイズ | 在庫状況 | 単価(税別) | |||
---|---|---|---|---|---|
サンプルについてお問い合わせ | |||||
1 mg | 在庫あり | ¥ 28,000 | |||
5 mg | 在庫あり | ¥ 53,500 | |||
10 mg | 在庫あり | ¥ 94,500 | |||
25 mg | 在庫あり | ¥ 157,500 | |||
50 mg | 在庫あり | ¥ 224,500 | |||
100 mg | 在庫あり | ¥ 303,000 |
説明 | Nemifitide acetate(173240-15-8 free base) (INN 00835 acetate) is a synthetic pentapeptide antidepressant with a potential for rapid onset of action. It is a peptide analog of melanocyte-inhibiting factor (MIF). |
In vitro | In-vitro studies indicate that both nemifitide and its active metabolite (M1) bind at micromolar concentrations to several receptors including the 5-HT2A, 5-HT2C, melanocortin MC4, MC5 and bombesin[3]. |
In vivo | Nemifitide (0.3 mg/kg; IP; daily; for 14 days) significantly increases swimming in the FSL rats after just 5 days of treatment and has long-lasting effect[2]. Nemifitide (0.0125-15.0 mg/kg) significantly increases swimming in the FSL rats at both low (0.025-0.3 mg/kg) and high (3.0-15.0 mg/kg) doses but not at intermediate (0.4-2.4 mg/kg) doses[2]. |
別名 | INN 00835 acetate |
分子量 | 754.85 |
分子式 | C35H47FN10O8 |
CAS No. | TP1127L1 |
keep away from moisture
Powder: -20°C for 3 years | In solvent: -80°C for 1 year
DMSO: 10 mM
You can also refer to dose conversion for different animals. 詳細
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Nemifitide acetate(173240-15-8 free base) TP1127L1 GPCR/G Protein Neuroscience 5-HT Receptor Nemifitide acetate(173240 15 8 free base) INN 00835 acetate INN00835 Acetate Nemifitide acetate(173240158 free base) INN 00835 Acetate INN-00835 Acetate Inhibitor inhibitor inhibit