store at low temperature,keep away from moisture
Powder: -20°C for 3 years | In solvent: -80°C for 1 year
Nitrosoglutathione (GSNO) is an endogenous transnitrosation donor involved in S-nitrosation of a variety of cellular proteins. GSNO, an exogenous NO donor and substrate of rat alcohol dehydrogenase class III isoenzyme, inhibits cerebral angiotensin II-dependent and -independent AT1 receptor responses.
パッケージサイズ | 在庫状況 | 単価(税別) | |||
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5 mg | 在庫あり | ¥ 11,000 | |||
10 mg | 在庫あり | ¥ 15,500 | |||
25 mg | 在庫あり | ¥ 24,500 | |||
50 mg | 在庫あり | ¥ 36,000 | |||
100 mg | 在庫あり | ¥ 52,500 | |||
500 mg | 在庫あり | ¥ 131,500 |
説明 | Nitrosoglutathione (GSNO) is an endogenous transnitrosation donor involved in S-nitrosation of a variety of cellular proteins. GSNO, an exogenous NO donor and substrate of rat alcohol dehydrogenase class III isoenzyme, inhibits cerebral angiotensin II-dependent and -independent AT1 receptor responses. |
In vitro | GSNO completely abolished the AngII-dependent AT1 receptor-mediated vasoconstriction of cerebral arteries. GSNO had no impact on responses to other vasoconstrictors sharing (phenylephrine, U46619) or not (5-HT) the same signalling pathway[1]. |
In vivo | Elevated blood pressure, proteinuria, and intrauterine growth restriction associated with PE were induced in Sprague-Dawley rats using L-NAME. These were partially reversed with the use of GSNO[3]. |
別名 | S-Nitrosoglutathione, SNOG, Glutathione thionitrite, GSNO |
分子量 | 336.32 |
分子式 | C10H16N4O7S |
CAS No. | 57564-91-7 |
store at low temperature,keep away from moisture
Powder: -20°C for 3 years | In solvent: -80°C for 1 year
DMSO: Soluble
H2O: 20 mg/ml(59.47 mM)
You can also refer to dose conversion for different animals. 詳細
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Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc.
Nitrosoglutathione 57564-91-7 Endocrinology/Hormones Immunology/Inflammation RAAS NO Synthase S-Nitrosoglutathione I/R RVC 588 SNOG Glutathione thionitrite inhibit antioxidant Inhibitor RVC-588 Angiotensin Receptor injury GSNO superoxide ischemia RVC588 inhibitor