Powder: -20°C for 3 years | In solvent: -80°C for 1 year
OAC1 (BAS 00287861) is a compound activating Octamer-binding transcription factor 4 (Oct4). It enhances the iPSC reprogramming efficiency and accelerates the reprogramming process.
説明 | OAC1 (BAS 00287861) is a compound activating Octamer-binding transcription factor 4 (Oct4). It enhances the iPSC reprogramming efficiency and accelerates the reprogramming process. |
キナーゼ試験 | Enzymology: Kinesin motor domains are expressed in Escherichia coli BL21(DE3) and purified. CENP-E proteins includes residues 2–340 with a carboxyl-terminal 6-his tag. All studies using MT are conducted in PEM25 buffer [25 mM PipesK+ (pH 6.8), 2 mM MgCl2, 1 mM EGTA] supplemented with 10 μM paclitaxel. The IC50 for steady-state inhibition is determined at 500 μM ATP, 5 μM MT, and 1 nM CENP-E in PEM25 buffer. |
細胞研究 | The Oct4-luc or Nanog-luc cells are treated with compound OAC1 at 1 μM concentration. Luciferase reporter assays are performed 24 h after OAC1 treatment.(Only for Reference) |
別名 | BAS 00287861 |
分子量 | 237.26 |
分子式 | C14H11N3O |
CAS No. | 300586-90-7 |
Powder: -20°C for 3 years | In solvent: -80°C for 1 year
Ethanol: 23.7 mg/mL (100 mM)
DMSO: 23.7 mg/mL (100 mM)
You can also refer to dose conversion for different animals. 詳細
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OAC1 300586-90-7 Membrane transporter/Ion channel OCT inhibit induced pluripotent stem cells HOXB4 Slc22a3 POU5F1 Oct3/4 Inhibitor human IMR90 fibroblast cells OAC 1 BAS00287861 BAS-00287861 CD34+cells BAS 00287861 Nanog promoters OAC-1 reprogramming inhibitor