Powder: -20°C for 3 years | In solvent: -80°C for 1 year
Oglemilast (GRC 3886) suppresses pulmonary cell infiltration, including eosinophilia and neutrophilia in vitro and in vivo. Oglemilast is an effective and orally active phosphodiesterase-4 (PDE4) inhibitor (IC50: 0.5 nM for PDE4D3). Oglemilast has the potential for inflammatory airway diseases.
パッケージサイズ | 在庫状況 | 単価(税別) | |||
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1 mg | 在庫あり | ¥ 14,000 | |||
5 mg | 在庫あり | ¥ 34,000 | |||
10 mg | 在庫あり | ¥ 58,000 | |||
25 mg | 在庫あり | ¥ 89,000 | |||
50 mg | 在庫あり | ¥ 114,000 | |||
100 mg | 在庫あり | ¥ 166,000 |
説明 | Oglemilast (GRC 3886) suppresses pulmonary cell infiltration, including eosinophilia and neutrophilia in vitro and in vivo. Oglemilast is an effective and orally active phosphodiesterase-4 (PDE4) inhibitor (IC50: 0.5 nM for PDE4D3). Oglemilast has the potential for inflammatory airway diseases. |
ターゲット&IC50 | PDE4D3:0.5 nM |
In vitro | For the PDE 4B1 and PDE 4D3 reporter cell lines, Oglemilast has EC50s of 11.4 nM, 4.4 nM, respectively[3]. |
別名 | GRC 3886 |
分子量 | 516.3 |
分子式 | C20H13Cl2F2N3O5S |
CAS No. | 778576-62-8 |
Powder: -20°C for 3 years | In solvent: -80°C for 1 year
DMSO: 3.6 mg/mL (7 mM), Sonication is recommended.
You can also refer to dose conversion for different animals. 詳細
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Oglemilast 778576-62-8 Metabolism PDE GRC-3886 GRC 3886 GRC3886 Inhibitor inhibitor inhibit