Powder: -20°C for 3 years | In solvent: -80°C for 1 year
Oxotremorine M iodide (Oxotremorine methiodide) is an agonist of mAChR and potentiates NMDA receptors.
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説明 | Oxotremorine M iodide (Oxotremorine methiodide) is an agonist of mAChR and potentiates NMDA receptors. |
In vitro | Oxotremorine M iodide robustly elicits a phosphoinositide response (EC50 = 0.22 μM). Oxotremorine M iodide shows EC50s of 0.36, 0.52, 1.62, and 1.48 μM for wild-type, M2, M3, and M2/M3 knockout mice, respectively[1]. Oxotremorine M iodide (0.1-30 μM) dose-dependently inhibits KCNQ2/3 currents[2]. |
In vivo | In male Sprague-Dawley albino rats, Oxotremorine M iodide (0.5 mg/kg; s.c.) increases DA release in the medial prefrontal cortex without affecting the nucleus accumbens[4]. |
別名 | Oxotremorine methiodide |
分子量 | 322.19 |
分子式 | C11H19IN2O |
CAS No. | 3854-04-4 |
Powder: -20°C for 3 years | In solvent: -80°C for 1 year
DMSO: 100 mg/mL (310.4 mM), Sonication is recommended.
You can also refer to dose conversion for different animals. 詳細
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Oxotremorine M iodide 3854-04-4 Neuroscience AChR Oxotremorine M Iodide Oxotremorine methiodide Inhibitor inhibitor inhibit