keep away from moisture
Powder: -20°C for 3 years | In solvent: -80°C for 1 year
PAR-4 Agonist Peptide, amide TFA (PAR-4-AP (TFA)), is a selective activator of the proteinase-activated receptor-4 (PAR-4), demonstrating specificity by not influencing PAR-1 or PAR-2, and its activity can be inhibited by a PAR-4 antagonist.
パッケージサイズ | 在庫状況 | 単価(税別) | |||
---|---|---|---|---|---|
サンプルについてお問い合わせ | |||||
1 mg | 在庫あり | ¥ 11,000 | |||
5 mg | 在庫あり | ¥ 34,000 | |||
10 mg | 在庫あり | ¥ 57,000 | |||
25 mg | 在庫あり | ¥ 96,000 | |||
50 mg | 在庫あり | ¥ 137,000 | |||
100 mg | 在庫あり | ¥ 198,000 | |||
1 mL * 10 mM (in DMSO) | 在庫あり | ¥ 54,000 |
説明 | PAR-4 Agonist Peptide, amide TFA (PAR-4-AP (TFA)), is a selective activator of the proteinase-activated receptor-4 (PAR-4), demonstrating specificity by not influencing PAR-1 or PAR-2, and its activity can be inhibited by a PAR-4 antagonist. |
In vivo | SCID mice demonstrate a markedly enhanced abdominal response to colorectal distension (CRD), with distension levels ranging from 0.04 to 0.1 mL amplifying the intensity of the EMG response from 384% to 132%, respectively, as compared to BALB/cBy controls (P<0.01; P<0.01; P<0.01; P<0.001). Activation of PAR-4 significantly mitigates this hypersensitivity (P<0.01, P<0.05; P<0.05; P<0.05)[1]. |
別名 | PAR-4-AP (TFA), AY-NH2 (TFA) |
分子量 | 794.82 |
分子式 | C36H49F3N8O9 |
CAS No. | 1228078-65-6 |
keep away from moisture
Powder: -20°C for 3 years | In solvent: -80°C for 1 year
H2O: 100 mg/mL (125.81 mM), Sonication is recommended.
DMSO: 250 mg/mL (314.54 mM)
You can also refer to dose conversion for different animals. 詳細
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PAR-4 Agonist Peptide, amide TFA 1228078-65-6 GPCR/G Protein Protease-activated Receptor PAR-4-AP (TFA) Thrombin receptors PAR4 Agonist Peptide, amide TFA Protease Activated Receptor (PAR) inhibit PAR-4 Agonist Peptide, amide Inhibitor PAR-4-AP PAR 4 Agonist Peptide, amide TFA AY-NH2 AY-NH2 (TFA) inhibitor