Powder: -20°C for 3 years | In solvent: -80°C for 1 year
PDE9-IN-1 is a selective and orally bioavailable Inhibitor of PDE9A(IC50 of 8.7 nM).
説明 | PDE9-IN-1 is a selective and orally bioavailable Inhibitor of PDE9A(IC50 of 8.7 nM). |
ターゲット&IC50 | PDE9A:8.7 nM |
In vivo | In the Unilateral common carotid artery occlusion (UCCAO) mouse model, PDE9-IN-1 (2.5-5.0 mg/kg; orally) significantly reduces the day 6 escape latency time, increases the frequency of platform area crossings, and recoveres learning and memory function. High dose group possibly improved the escape latency time of mice[1]. |
分子量 | 362.4 |
分子式 | C17H23FN6O2 |
CAS No. | 2305087-92-5 |
Powder: -20°C for 3 years | In solvent: -80°C for 1 year
DMSO: 45 mg/mL (124.17 mM)
You can also refer to dose conversion for different animals. 詳細
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PDE9-IN-1 2305087-92-5 Metabolism PDE PDE-9-IN-1 PDE9IN1 PDE9 IN 1 Inhibitor inhibitor inhibit