Powder: -20°C for 3 years | In solvent: -80°C for 1 year
PF-429242 is a competitive inhibitor of sterol regulatory element-binding protein (SREBP) site 1 protease (IC50 = 0.175 μM). It is selective for site 1 protease against a panel of serine proteases. PF-429242 inhibits rate of cholesterol synthesis in CHO cells (IC50 = 0.53 μM).
パッケージサイズ | 在庫状況 | 単価(税別) |
---|---|---|
1 mg | 在庫あり | ¥ 8,500 |
2 mg | 在庫あり | ¥ 11,500 |
5 mg | 在庫あり | ¥ 23,000 |
10 mg | 在庫あり | ¥ 42,000 |
25 mg | お問い合わせ | ¥ 93,000 |
50 mg | お問い合わせ | ¥ 135,500 |
100 mg | お問い合わせ | ¥ 197,500 |
1 mL * 10 mM (in DMSO) | 在庫あり | ¥ 23,000 |
説明 | PF-429242 is a competitive inhibitor of sterol regulatory element-binding protein (SREBP) site 1 protease (IC50 = 0.175 μM). It is selective for site 1 protease against a panel of serine proteases. PF-429242 inhibits rate of cholesterol synthesis in CHO cells (IC50 = 0.53 μM). |
ターゲット&IC50 | SREBP:0.175 μM |
分子量 | 409.56 |
分子式 | C25H35N3O2 |
CAS No. | 947303-87-9 |
Powder: -20°C for 3 years | In solvent: -80°C for 1 year
DMSO: 24.1 mg/mL(50 mM)
You can also refer to dose conversion for different animals. 詳細
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PF 429242 947303-87-9 Membrane transporter/Ion channel Metabolism NPC1L1 Lipid PF-429242 PF429242 Inhibitor inhibitor inhibit