Powder: -20°C for 3 years | In solvent: -80°C for 1 year
PPTN is a high-affinity, competitive and highly selective antagonist of P2Y14 receptor(KB value of 434 pM), with anti-inflammatory and immune activity.
パッケージサイズ | 在庫状況 | 単価(税別) | |||
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1 mg | 在庫あり | ¥ 45,000 | |||
5 mg | 在庫あり | ¥ 103,000 | |||
10 mg | 在庫あり | ¥ 151,500 | |||
25 mg | 在庫あり | ¥ 226,500 | |||
50 mg | 在庫あり | ¥ 319,000 | |||
100 mg | 在庫あり | ¥ 431,500 | |||
500 mg | 在庫あり | ¥ 867,500 |
説明 | PPTN is a high-affinity, competitive and highly selective antagonist of P2Y14 receptor(KB value of 434 pM), with anti-inflammatory and immune activity. |
ターゲット&IC50 | P2Y14 receptor:434 pM (KB) |
In vitro | PPTN exhibits strong selectivity for the P2Y14-R over the other seven nucleotide-activated P2Y receptors. PPTN inhibits UDP-glucose-promoted chemotaxis in differentiated HL-60 human promyelocytic leukemia cells with IC50s of ~1 nM in the presence of 10 μM UDP-glucose and ~4 nM in the presence of 100 μM[1]. |
分子量 | 475.5 |
分子式 | C29H24F3NO2 |
CAS No. | 1160271-30-6 |
Powder: -20°C for 3 years | In solvent: -80°C for 1 year
DMSO: Insoluble
You can also refer to dose conversion for different animals. 詳細
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PPTN 1160271-30-6 GPCR/G Protein Neuroscience P2Y Receptor Inhibitor inhibitor inhibit