Powder: -20°C for 3 years | In solvent: -80°C for 1 year
PU 23 is an inhibitor of multidrug-resistant protein 4 (MRP4).
説明 | PU 23 is an inhibitor of multidrug-resistant protein 4 (MRP4). |
In vitro | 6-Mercaptopurine (6-MP) inhibits HEK293 and HEK293/MRP4 cells with IC50s of 2.81 and 14.11 μM, respectively. The combination of PU23 and 6-MP inhibits HEK293 and HEK293/MRP4 cells with IC50s of 1.84 and 6.06 μM, respectively.Preincubation of HEK293/MRP4 cells with PU 23 (50 μM) for 2 h also significantly increases the amount of 6-MP in cells [1]. |
分子量 | 425.52 |
分子式 | C21H19N3O3S2 |
CAS No. | 817635-93-1 |
Powder: -20°C for 3 years | In solvent: -80°C for 1 year
DMSO: 55 mg/mL (129.25 mM)
You can also refer to dose conversion for different animals. 詳細
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PU23 817635-93-1 Immunology/Inflammation MRP MRP4 resistance Inhibitor inhibit protein 6-Mercaptopurine PU-23 multidrug PU 23 inhibitor