Powder: -20°C for 3 years | In solvent: -80°C for 1 year
Quinoclamine is a naphthoquinone derivative and is an NF-κB inhibitor.
パッケージサイズ | 在庫状況 | 単価(税別) | |||
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10 mg | 在庫あり | ¥ 7,000 | |||
25 mg | 在庫あり | ¥ 10,000 | |||
50 mg | 在庫あり | ¥ 15,000 | |||
100 mg | 在庫あり | ¥ 21,500 | |||
500 mg | 在庫あり | ¥ 52,500 | |||
1 mL * 10 mM (in DMSO) | 在庫あり | ¥ 11,500 |
説明 | Quinoclamine is a naphthoquinone derivative and is an NF-κB inhibitor. |
In vitro | Quinoclamine induces the differentiation of U-937 cells into macrophage-like cells. Quinoclamine inhibits NF-κB activities in HepG2 cells (IC50: 1.7 μM). Quinoclamine inhibits induced NF-κB activities in lung and breast cancer cell lines. Quinoclamine affects the expression levels of genes involved in cell cycle or apoptosis. Quinoclamine down-regulates the expressions of UDP glucuronosyltransferase genes involved in phase II drug metabolism. Quinoclamine (1-4 μM; 30 minutes ) inhibits endogenous NF-κB activity in HepG2 cells through the inhibition of IκB-α phosphorylation and p65 translocation [1][2]. |
分子量 | 207.61 |
分子式 | C10H6ClNO2 |
CAS No. | 2797-51-5 |
Powder: -20°C for 3 years | In solvent: -80°C for 1 year
DMSO: 50 mg/mL (240.84 mM), Sonication is recommended.
You can also refer to dose conversion for different animals. 詳細
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Quinoclamine 2797-51-5 NF-Κb NF-κB Nuclear factor-κB derivative inhibit Inhibitor Nuclear factor-kappaB naphthoquinone inhibitor