Powder: -20°C for 3 years | In solvent: -80°C for 1 year
RBN012759, a potent and selective PARP14 inhibitor, decreases pro-tumor macrophage function and elicits inflammatory responses in tumor explants.
説明 | RBN012759, a potent and selective PARP14 inhibitor, decreases pro-tumor macrophage function and elicits inflammatory responses in tumor explants. |
ターゲット&IC50 | PARP5b:10 μM (IC50), PARP11:1 μM (IC50), PARP6:4 μM (IC50), PARP14:<3 nM (IC50), PARP12:5 μM (IC50), PARP16:6 μM (IC50), PARP15:3 μM (IC50), PARP5a:8 μM (IC50), PARP10:1 μM (IC50), PARP7:4 μM (IC50), PARP4:10 μM (IC50), PARP8:20 μM (IC50) |
分子量 | 378.46 |
分子式 | C19H23FN2O3S |
CAS No. | 2360851-29-0 |
Powder: -20°C for 3 years | In solvent: -80°C for 1 year
DMSO: 12 mg/mL (31.71 mM)
You can also refer to dose conversion for different animals. 詳細
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Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc.
RBN012759 2360851-29-0 Chromatin/Epigenetic DNA Damage/DNA Repair PARP poly ADP ribose polymerase pro-tumor cancer PARP14 macrophage RBN-012759 RBN 012759 Inhibitor inflammatory inhibit inhibitor