Powder: -20°C for 3 years | In solvent: -80°C for 1 year
Ribocil is a highly selective chemical modulator of bacterial riboflavin riboswitches. Ribocil strongly inhibits GFP expression, achieving a 50% effective concentration (EC50: 0.3 μM).
説明 | Ribocil is a highly selective chemical modulator of bacterial riboflavin riboswitches. Ribocil strongly inhibits GFP expression, achieving a 50% effective concentration (EC50: 0.3 μM). |
In vitro | Ribocil is a highly specific bioactive synthetic mimic of FMN, which competes with the natural ligand to inhibit FMN riboswitch-mediated expression of ribB and inhibits bacterial growth. Ribocil-B shows superior microbiological activity as compared to Ribocil-A (minimum inhibitory concentration (MIC) = 1 μg/ml versus MIC ≥ 64 μg/ml), inhibition of riboflavin synthesis (IC50 = 0.13 μM versus IC50 > 26 μM), and binding affinity to the E. coli FMN aptamer (Kd = 6.6 nM versus Kd ≥ 10,000 nM) [1] |
分子量 | 382.48 |
分子式 | C19H22N6OS |
CAS No. | 1381289-58-2 |
Powder: -20°C for 3 years | In solvent: -80°C for 1 year
DMSO: 24.8 mg/mL (64.84 mM)
You can also refer to dose conversion for different animals. 詳細
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Ribocil 1381289-58-2 Microbiology/Virology Antibacterial Inhibitor Bacterial inhibit inhibitor