Powder: -20°C for 3 years | In solvent: -80°C for 1 year
Sparfloxacin (CI-978) is a fluoroquinolone antibiotic that inhibits bacterial DNA gyrase, thereby inhibiting DNA replication and transcription.
パッケージサイズ | 在庫状況 | 単価(税別) | |||
---|---|---|---|---|---|
サンプルについてお問い合わせ | |||||
50 mg | 在庫あり | ¥ 10,000 | |||
100 mg | 在庫あり | ¥ 13,000 | |||
200 mg | 在庫あり | ¥ 18,000 | |||
500 mg | 在庫あり | ¥ 27,500 | |||
1 mL * 10 mM (in DMSO) | 在庫あり | ¥ 11,500 |
説明 | Sparfloxacin (CI-978) is a fluoroquinolone antibiotic that inhibits bacterial DNA gyrase, thereby inhibiting DNA replication and transcription. |
In vitro | Orally administered Sparfloxacin produces favorable therapeutic outcomes in mice with systemic infections caused by Staphylococcus aureus, Streptococcus pyogenes, Streptococcus pneumoniae, Escherichia coli, and Pseudomonas aeruginosa. |
In vivo | Sparfloxacin targets DNA gyrase, inhibiting DNA synthesis. It exhibits potent, broad-spectrum antimicrobial activity, effective against Gram-positive bacteria such as Staphylococcus, Streptococcus, and Enterococcus species (MIC=0.1 to 0.78μg/ml), Gram-negative bacteria including Enterobacteriaceae and Pseudomonas species (MIC=0.0125 to 1.56μg/ml), glucose non-fermenters (MIC=0.025 to 0.78μg/ml), Legionella (MIC=0.0125 to 0.05μg/ml), and anaerobes (MIC=0.2 to 0.78μg/ml). |
別名 | AT-4140, PD 131501, Zagam, CI-978 |
分子量 | 392.4 |
分子式 | C19H22F2N4O3 |
CAS No. | 110871-86-8 |
Powder: -20°C for 3 years | In solvent: -80°C for 1 year
DMSO: 9 mg/mL (22.93 mM)
Ethanol: < 1 mg/mL (insoluble or slightly soluble)
H2O: < 1 mg/mL (insoluble or slightly soluble)
You can also refer to dose conversion for different animals. 詳細
bottom
Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc.
Sparfloxacin 110871-86-8 DNA Damage/DNA Repair Microbiology/Virology Antibacterial Topoisomerase DNA gyrase Antibiotic CI978 AT 4140 AT-4140 AT4140 Inhibitor inhibit PD 131501 Zagam PD131501 Bacterial PD-131501 CI 978 CI-978 inhibitor