Powder: -20°C for 3 years | In solvent: -80°C for 1 year
Rislenemdaz (CERC-301) (CERC-301) is an antagonist of the N-methyl-D-aspartate (NMDA) receptor subunit 2B (GluN2B).
説明 | Rislenemdaz (CERC-301) (CERC-301) is an antagonist of the N-methyl-D-aspartate (NMDA) receptor subunit 2B (GluN2B). |
ターゲット&IC50 | NMDAR 2B:3.6 nM, GluN2B:8.1 nM (ki), GluN2B:3.6 nM |
In vitro | rislemdaz (CERC-301) inhibited calcium influx in agonist stimulated NMDA-GluN1a/GluN2B L(tk-) cells. rislemdaz (CERC-301) had an IC50 of 3.6 nM. rislemdaz is highly selective for GluN2B receptors. rislemdaz showed minimal activity against sigma-type receptors at a concentration of 10 uM[1]. |
別名 | CERC-301, MK-0657 |
分子量 | 358.41 |
分子式 | C19H23FN4O2 |
CAS No. | 808732-98-1 |
Powder: -20°C for 3 years | In solvent: -80°C for 1 year
DMSO: 90.0 mg/mL (251.1 mM), Sonication is recommended.
You can also refer to dose conversion for different animals. 詳細
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Rislenemdaz 808732-98-1 Membrane transporter/Ion channel Neuroscience iGluR CERC301 MK 0657 CERC-301 MK-0657 CERC 301 MK0657 Inhibitor inhibitor inhibit