Powder: -20°C for 3 years | In solvent: -80°C for 1 year
SR8278 is an REV-ERBα antagonist(EC50 = 0.47 μM), blocking activation of the receptor by the synthetic agonist GSK 4112
パッケージサイズ | 在庫状況 | 単価(税別) | |||
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サンプルについてお問い合わせ | |||||
1 mg | 在庫あり | ¥ 12,000 | |||
5 mg | 在庫あり | ¥ 28,500 | |||
10 mg | 在庫あり | ¥ 45,500 | |||
50 mg | 在庫あり | ¥ 105,500 | |||
1 mL * 10 mM (in DMSO) | 在庫あり | ¥ 31,500 |
説明 | SR8278 is an REV-ERBα antagonist(EC50 = 0.47 μM), blocking activation of the receptor by the synthetic agonist GSK 4112 |
In vitro | SR8278 stimulates the expression of two REV-ERBα target genes involved in the regulation of glucose production, glucose 6-phosphatase and phosphoenolpyruvate carboxykinase, in liver cells[1] |
分子量 | 361.48 |
分子式 | C18H19NO3S2 |
CAS No. | 1254944-66-5 |
Powder: -20°C for 3 years | In solvent: -80°C for 1 year
DMSO: 50 mg/mL (138.32 mM,), Sonication is recommended.
You can also refer to dose conversion for different animals. 詳細
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SR8278 1254944-66-5 Others SR-8278 SR 8278 Duchenne muscular dystrophy inhibit metabolism biological rhythm Alzheimer's disease neurosurgery Inhibitor REV-ERBα REV-ERB inhibitor