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Search Results for " metabolism "

ターゲット

Mitochondrial Metabolism Mitochondrial Metabolism

470

阻害剤

197

天然化合物

172

リコンビナントタンパク質

ライブラリー

カタログ番号	製品名	別名	ターゲット
T9372	D-Histidine		Mitochondrial Metabolism
	D-Histidine is an enantiomer of L-histidine. L-Histidine is an inhibitor of mitochondrial glutamine transport and also an essential amino acid for infants.		Mitochondrial Metabolism
T15373	Gboxin		ATPase , Mitochondrial Metabolism
	Gboxin is an inhibitor of oxidative phosphorylation that targets glioblastoma,inhibits the activity of F0F1 ATP synthase, with antitumour activity.		ATPase , Mitochondrial Metabolism
T9777	THP104c		Mitochondrial Metabolism
	THP104c is an inhibitor of mitochondrial fission.		Mitochondrial Metabolism
T12408	Perhexiline maleate		Others , Mitochondrial Metabolism
	Perhexiline maleate is an orally active inhibitor of CPT1 and CPT2 that reduces fatty acid metabolism. The IC50 values of perhexiline maleate against rat heart and liver CPT 1 were 77 and 148 μM, respectively.		Others , Mitochondrial Metabolism
T15241	ER-000444793		Others , Mitochondrial Metabolism
	ER-000444793 is a potent mitochondrial permeability transition pore (mPTP) opening inhibitor and it also inhibits mPTP (IC50: 2.8 μM).		Others , Mitochondrial Metabolism
T14497	BAM 15		OXPHOS , Mitochondrial Metabolism
	BAM 15 is an uncoupler of mitochondrial protonophore.		OXPHOS , Mitochondrial Metabolism
T10706	CCI-006		Mitochondrial Metabolism
	CCI-006, a selective inhibitor and chemosensitizer for MLL-rearranged leukemia cells, disrupts mitochondrial respiration. This action leads to irreversible mitochondrial depolarization and triggers a pro-apoptotic unfold...		Mitochondrial Metabolism
T19428	Mito-TEMPO		Reactive Oxygen Species , Mitochondrial Metabolism
	Mito-TEMPO is a mitochondria-targeted superoxide dismutase mimetic. Mito-TEMPO scavenges superoxide and alkyl radicals and prevents mitochondrial oxidation, necrosis and apoptosis.		Reactive Oxygen Species , Mitochondrial Metabolism
T9169	MPP+ iodide		Mitochondrial Metabolism , Autophagy
	MPP+ iodide, the metabolite of a neurotoxin MPTP, causes symptom of Parkinson's disease (PD) in animal models by selectively destroying dopaminergic neurons in substantia nigra. MPP+ induces dopamine transporter (DAT) ex...		Mitochondrial Metabolism , Autophagy
T1768	7ACC2		Mitochondrial Metabolism , Monocarboxylate transporter
	7ACC2 is a new potent MCT inhibitor with IC50 of 11 nM for [14C]-lactate influx; new antitumor treatment targeting lactate transport in Y cells.		Mitochondrial Metabolism , Monocarboxylate transporter
T8734	Choline		Others
	Choline is a ubiquitous water soluble nutrient, often associated with the B vitamins		Others
T4639	Azemiglitazone	MSDC 0602	Mitochondrial Metabolism , mTOR
	Azemiglitazone (MSDC 0602) is an insulin sensitizer potentially for the treatment of diabetes.		Mitochondrial Metabolism , mTOR
T9031	MCU-i4		Others , Mitochondrial Metabolism
	MCU-i4 is a novel negative modulator of the MCU, binding MICU1 and impairing muscle cell growth.		Others , Mitochondrial Metabolism
T40514	2,2,14,14-Tetramethyl-8-oxopentadecanedioic acid		Others
	2,2,14,14-Tetramethyl-8-oxopentadecanedioic acid is a ketone compound, compound example II-9. 2,2,14,14-Tetramethyl-8-oxopentadecanedioic acid can be used for the research of cardiovascular diseases, dysproteinemias, dys...		Others
T3713	BAY-876		transporter
	BAY-876 is an orally active and selective inhibitor of glucose transporter 1 (GLUT1, IC50= 2 nM). BAY-876 exhibits >130-fold more selective for GLUT1 than GLUT2, GLUT3, and GLUT4. BAY-876 also inhibits glycolytic metabol...		transporter
T2498	Adjudin	AF-2364	Chloride channel , Mitochondrial Metabolism
	Adjudin (AF-2364) is a small molecule compound known to possess antispermatogenic function, attenuates microglia activation by suppression of the NF-κB pathway.		Chloride channel , Mitochondrial Metabolism
T16342	KL1333	NQO1 activator 1	NADPH , Mitochondrial Metabolism
	KL1333 (NQO1 activator 1) enhances energy metabolism and mitochondrial dysfunction in MELAS fibroblasts. Elevated NAD+ levels trigger the activation of SIRT1 and AMPK, and subsequently activates PGC-1α. NQO1 activator 1 ...		NADPH , Mitochondrial Metabolism
T4039	BIBB 515		Others
	BIBB 515 is a selective and potent inhibitor of OSC in vivo with an ED50 value of 0.2-0.5 and 0.36-33.3 mg/kg in rats and mice, respectively. 2, 3-Oxidosqualene cyclase (OSC) is an important enzyme in the biosynthesis of...		Others
T6816	DASA-58		PKM
	DASA-58 is a specific and potent Pyruvate kinase M2 (PKM2) activator.		PKM
T8732	CTPI-2		Others , Mitochondrial Metabolism
	CTPI-2 is an inhibitor of mitochondrial citrate carrier SLC25A1 with(KD : 3.5 μM). CTPI-2 inhibits glycolysis, PPARγ, and its downstream target the glucose transporter GLUT4. CTPI-2 exhibits anti-tumor activity.CTPI-2 ha...		Others , Mitochondrial Metabolism
T8500	VLX600		OXPHOS , Mitochondrial Metabolism , Autophagy
	VLX600 is an iron-chelating oxidative phosphorylation (OXPHOS) inhibitor, is a cell-permeable anticancer agent. It acts by reducing mitochondrial oxidative phosphorylation in tumor cells.		OXPHOS , Mitochondrial Metabolism , Autophagy
T6834	FCCP	Carbonyl cyanide 4-(trifluoromethoxy)phenylhydrazone,Trifluoromethoxy carbonylcyanide phenylhydrazone	ATPase , Mitochondrial Metabolism
	FCCP (Trifluoromethoxy carbonylcyanide phenylhydrazone) is an oxidative phosphorylation (OXPHOS) inhibitor and mitochondrial proton carrier uncoupler. FCCP is often used as an apoptosis inducer.		ATPase , Mitochondrial Metabolism
T7093	Rafoxanide		CDK , Parasite
	Rafoxanide as a dual CDK4/6 inhibitor for the treatment of skin cancer. Rafoxanide is a salicylanilide used as an anthelmintic. It is used to treat fluke, hookworm and other infestations.		CDK , Parasite
T7837	SR8278		Others
	SR8278 is an REV-ERBα antagonist(EC50 = 0.47 µM), blocking activation of the receptor by the synthetic agonist GSK 4112		Others
T2367	SKF-86002	SKF86002	p38 MAPK , TNF
	SKF-86002 is an effective inhibitor of p38 MAP kinase (IC50: 0.5-1 uM); inhibits LPS-induced IL-1 and TNF-α production in human monocytes (IC50: 1 μM).		p38 MAPK , TNF
T7835	CM10	CM 10	Dehydrogenase
	CM10 is an aldehyde dehydrogenase 1A family(ALDH1A) inhibitor.		Dehydrogenase
T8308	NL-1		Mitochondrial Metabolism , Autophagy
	NL-1 is a mitoNEET inhibitor with antileukemic effect.		Mitochondrial Metabolism , Autophagy
T8366	Mitochonic acid 5	MA-5	Mitochondrial Metabolism
	Mitochonic acid 5 (MA-5) is a derivative of the plant hormone indole-3-acetic acid. Mitochonic acid 5 binds mitochondria and ameliorates renal tubular and cardiac myocyte damage.It has been shown to improve survival of f...		Mitochondrial Metabolism
T9232	Mitochondrial fusion promoter M1		Mitochondrial Metabolism
	Mitochondrial fusion promoter M1, a modulator of mitochondrial dynamics, enhances mitochondrial function and cellular respiration, and has shown efficacy in reducing brain and cardiac damage in rats suffering from cardia...		Mitochondrial Metabolism
T4441	UK-5099	UK 5099,PF-1005023,UK5099	Others , Mitochondrial Metabolism
	UK-5099 (PF-1005023) is a specific and potent inhibitor of MPC carrier activity [1]. It potently inhibits pyruvate-dependent oxygen consumption by rat heart mitochondria (IC50: 50 nM) [1].		Others , Mitochondrial Metabolism
T8676	FOY 251		Others , Serine/threonin kinase , SARS-CoV
	FOY 251 is a proteinase inhibitor, and is an anti-proteolytic active metabolite camostate.		Others , Serine/threonin kinase , SARS-CoV
T6157	Devimistat	CPI-613,CPI613,CPI 613,6,8-Bis(benzylthio)octanoic acid	Apoptosis , Dehydrogenase , Mitochondrial Metabolism
	Devimistat (6,8-Bis(benzylthio)octanoic acid) , a lipoate analog, inhibits mitochondrial enzymes pyruvate dehydrogenase (PDH) and α-ketoglutarate dehydrogenase, disrupts tumor cell mitochondrial metabolism. It has potent...		Apoptosis , Dehydrogenase , Mitochondrial Metabolism
T5827	BI-6C9		Apoptosis , Others , Mitochondrial Metabolism
	BI-6C9 is an inhibitor of tBid (Kd = 20 µM).BI-6c9 prevented MOMP and mitochondrial fission, and protected the cells from cell death.		Apoptosis , Others , Mitochondrial Metabolism
T12148	N-Desmethyltamoxifen hydrochloride		Estrogen Receptor/ERR , Endogenous Metabolite , PKC
	N-Desmethyltamoxifen hydrochloride is the major tamoxifen metabolite in humans.		Estrogen Receptor/ERR , Endogenous Metabolite , PKC
T9211	Mito-LND	Mito-Loidamine	OXPHOS , Reactive Oxygen Species , Mitochondrial Metabolism , Autophagy
	Mito-LND (Mito-Loidamine) is an orally active and mitochondria-targeted inhibitor of oxidative phosphorylation.
T0412	Idebenone	CV-2619	Apoptosis , Antioxidant , Mitochondrial Metabolism
	Idebenone (CV-2619) is a synthetic analogue of ubiquinone (Coenzyme Q10), a vital cell antioxidant and essential component of the Electron Transport Chain (ETC).		Apoptosis , Antioxidant , Mitochondrial Metabolism
T7629	Olesoxime	NSC 21311,TRO 19622	Mitochondrial Metabolism
	Olesoxime (TRO 19622) (TRO19622), A Mitochondrial-Targeted Neuroprotective Compound,is an experimental neuroprotective drug.		Mitochondrial Metabolism
T3124	Carbendazim	Bavistin,Carbendazole,Mercarzole	Antifungal
	Carbendazim (Mercarzole) is a broad-spectrum benzimidazole antifungal with potential antimitotic and antineoplastic activities. Although the exact mechanism of action is unclear, carbendazim appears to binds to an unspec...		Antifungal
T5363	Tempo	2,2,6,6-Tetramethylpiperidinooxy	Free radical scavengers , Reactive Oxygen Species , DNA/RNA Synthesis , Mitochondrial Metabolism
	Tempo (2,2,6,6-Tetramethylpiperidinooxy) has a wide range of applications including use as a free radical scavenger, a reagent in organic synthesis and as a structural probe in electron spin resonance spectroscopy.
T5337	IACS-010759	IACS-10759,IACS 10759,IACS10759	Apoptosis , Others , Mitochondrial Metabolism
	IACS-010759 is an orally bioavailable inhibitor of complex I of oxidative phosphorylation of the mitochondrial electron transport chain.		Apoptosis , Others , Mitochondrial Metabolism
T0849	Pyrimethamine	Pirimecidan,RP 4753,Pirimetamin	DHFR , Antifolate , Parasite
	Pyrimethamine (Pirimecidan) is a competitive inhibitor of dihydrofolate reductase (DHFR), used as an antimalarial drug.		DHFR , Antifolate , Parasite
T8766	GOT1 inhibitor-1	GOT1 inhibitor 2c	Others
	GOT1 inhibitor-1 (GOT1 inhibitor 2c) is a novel, potent and non-covalent inhibitor of glutamate oxaloacetate transaminase 1 (GOT1) with an IC50 of 8.2 uM.		Others
T24656	PQ-10	A844337,PQ 10,A-844337,A 844337	PDE
	PQ-10 (A-844337) is a PDE-10 inhibitor. PQ-10 induces brain glucose metabolism patterns, which may be a potential translational biomarker.		PDE
T0239	Lonidamine	AF1890,DICA,Diclondazolic Acid	Apoptosis , Hexokinase , Mitochondrial Metabolism
	Lonidamine (Diclondazolic Acid) is an indazole carboxylic acid derivative, principally inhibiting aerobic glycolytic activity, by its effect on mitochondrially-bound hexokinase (HK).		Apoptosis , Hexokinase , Mitochondrial Metabolism
T2607	MSDC 0160	CAY10415,Mitoglitazone,MSDC0160,MSDC-0160	Others , IGF-1R , Mitochondrial Metabolism
	MSDC 0160 (CAY10415) is a prototype mTOT-modulating insulin sensitizer being used in trials studying the treatment of Type 2 Diabetes and Alzheimer's Disease.		Others , IGF-1R , Mitochondrial Metabolism
T10814	Cinacalcet metabolite M4	Rarechem AL BW 1078	Calcium Channel
	Cinacalcet metabolite M4 (Rarechem AL BW 1078) is a metabolite of Cinacalcet. Cinacalcet is an allosteric agonist of Ca receptor.		Calcium Channel
T35343	MTI-31	MTI-31,LXI-15029	mTOR
	MTI-31 (LXI-15029) is a potent, orally active and highly selective inhibitor of mTORC1 and mTORC2. MTI-31 is selective for mTOR (Kd: 0.20 nM) versus PIK3CA, PIK3CB and PIK3G with >5,000 fold selectivity in mTOR binding a...		mTOR
T1640	Ciprofloxacin	Ciproxan,Ciprobay,Bay o 9867,Bay-09867	Topoisomerase , Antibacterial , Antibiotic
	Ciprofloxacin (Bay-09867), a synthetic broad spectrum fluoroquinolone antibiotic, inhibits bacterial DNA gyrase. It is more active against Gram-negative bacteria than Gram-positive bacteria.		Topoisomerase , Antibacterial , Antibiotic
T9235	GW604714X	2,4-Thiazolidinedione, 5-[[5-[6-(4-acetyl-1-piperazinyl)-3-nitro-2-pyridinyl]-2-fluorophenyl]methylene]-	Mitochondrial Metabolism
	GW604714X (2,4-Thiazolidinedione, 5-[[5-[6-(4-acetyl-1-piperazinyl)-3-nitro-2-pyridinyl]-2-fluorophenyl]methylene]-) were found to be potent inhibitors of mitochondrial respiration supported by pyruvate		Mitochondrial Metabolism
T7487	Speract		Others , Mitochondrial Metabolism
	Speract, a peptide from sea urchin eggs, regulates sperm motility and stimulates sperm mitochondrial metabolism.		Others , Mitochondrial Metabolism

Compounds

D-Histidine

T9372

Synonym:

Target: Mitochondrial Metabolism

Gboxin

T15373

Synonym:

Target: ATPase, Mitochondrial Metabolism

THP104c

T9777

Synonym:

Target: Mitochondrial Metabolism

Perhexiline maleate

T12408

Synonym:

Target: Others, Mitochondrial Metabolism

ER-000444793

T15241

Synonym:

Target: Others, Mitochondrial Metabolism

BAM 15

T14497

Synonym:

Target: OXPHOS, Mitochondrial Metabolism

CCI-006

T10706

Synonym:

Target: Mitochondrial Metabolism

Mito-TEMPO

T19428

Synonym:

Target: Reactive Oxygen Species, Mitochondrial Metabolism

MPP+ iodide

T9169

Synonym:

Target: Mitochondrial Metabolism, Autophagy

7ACC2

T1768

Synonym:

Target: Mitochondrial Metabolism, Monocarboxylate transporter

Target: Mitochondrial Metabolism, mTOR

MCU-i4

T9031

Synonym:

Target: Others, Mitochondrial Metabolism

2,2,14,14-Tetramethyl-8-oxopentadecanedioic acid

Target: Chloride channel, Mitochondrial Metabolism

KL1333

T16342

Synonym: NQO1 activator 1

Target: NADPH, Mitochondrial Metabolism

Target: Others, Mitochondrial Metabolism

VLX600

T8500

Synonym:

Target: OXPHOS, Mitochondrial Metabolism, Autophagy

FCCP

T6834

Synonym: Carbonyl cyanide 4-(trifluoromethoxy)phenylhydrazone,Trifluoromethoxy carbonylcyanide phenylhydrazone

Target: ATPase, Mitochondrial Metabolism

Rafoxanide

T7093

Synonym:

Target: CDK, Parasite

Target: p38 MAPK, TNF

CM10

T7835

Synonym: CM 10

Target: Dehydrogenase

NL-1

T8308

Synonym:

Target: Mitochondrial Metabolism, Autophagy

Mitochonic acid 5

T8366

Synonym: MA-5

Target: Mitochondrial Metabolism

Mitochondrial fusion promoter M1

T9232

Synonym:

Target: Mitochondrial Metabolism

UK-5099

T4441

Synonym: UK 5099,PF-1005023,UK5099

Target: Others, Mitochondrial Metabolism

FOY 251

T8676

Synonym:

Target: Others, Serine/threonin kinase, SARS-CoV

Devimistat

T6157

Synonym: CPI-613,CPI613,CPI 613,6,8-Bis(benzylthio)octanoic acid

Target: Apoptosis, Dehydrogenase, Mitochondrial Metabolism

BI-6C9

T5827

Synonym:

Target: Apoptosis, Others, Mitochondrial Metabolism

N-Desmethyltamoxifen hydrochloride

T12148

Synonym:

Target: Estrogen Receptor/ERR, Endogenous Metabolite, PKC

Mito-LND

T9211

Synonym: Mito-Loidamine

Target: OXPHOS, Reactive Oxygen Species, Mitochondrial Metabolism, Autophagy

Idebenone

T0412

Synonym: CV-2619

Target: Apoptosis, Antioxidant, Mitochondrial Metabolism

Olesoxime

T7629

Synonym: NSC 21311,TRO 19622

Target: Mitochondrial Metabolism

Carbendazim

T3124

Synonym: Bavistin,Carbendazole,Mercarzole

Target: Antifungal

Tempo

T5363

Synonym: 2,2,6,6-Tetramethylpiperidinooxy

Target: Free radical scavengers, Reactive Oxygen Species, DNA/RNA Synthesis, Mitochondrial Metabolism

IACS-010759

T5337

Synonym: IACS-10759,IACS 10759,IACS10759

Target: Apoptosis, Others, Mitochondrial Metabolism

Pyrimethamine

T0849

Synonym: Pirimecidan,RP 4753,Pirimetamin

Target: DHFR, Antifolate, Parasite

GOT1 inhibitor-1

T8766

Synonym: GOT1 inhibitor 2c

Target: Others

PQ-10

T24656

Synonym: A844337,PQ 10,A-844337,A 844337

Target: PDE

Lonidamine

T0239

Synonym: AF1890,DICA,Diclondazolic Acid

Target: Apoptosis, Hexokinase, Mitochondrial Metabolism

MSDC 0160

T2607

Synonym: CAY10415,Mitoglitazone,MSDC0160,MSDC-0160

Target: Others, IGF-1R, Mitochondrial Metabolism

Cinacalcet metabolite M4

T10814

Synonym: Rarechem AL BW 1078

Target: Calcium Channel

MTI-31

T35343

Synonym: MTI-31,LXI-15029

Target: mTOR

Ciprofloxacin

T1640

Synonym: Ciproxan,Ciprobay,Bay o 9867,Bay-09867

Target: Topoisomerase, Antibacterial, Antibiotic

GW604714X

T9235

Synonym: 2,4-Thiazolidinedione, 5-[[5-[6-(4-acetyl-1-piperazinyl)-3-nitro-2-pyridinyl]-2-fluorophenyl]methylene]-

Target: Mitochondrial Metabolism

Speract

T7487

Synonym:

Target: Others, Mitochondrial Metabolism

カタログ番号	製品名	別名	ターゲット
TN1586	Dihydrorotenone		Apoptosis , Mitochondrial Metabolism
	Dihydrorotenone is a potent mitochondrial inhibitor and probably induces Parkinsonian syndrome.		Apoptosis , Mitochondrial Metabolism
T10857	Coenzyme A		Endogenous Metabolite
	Coenzyme A is an obligatory cofactor in all living cells synthesized from pantothenate (Vitamin B5), adenosine triphosphate (ATP), and cysteine.		Endogenous Metabolite
T8433	HQNO		Mitochondrial Metabolism
	HQNO is a natural product isolated from P. aeruginosa,and is a potent inhibitor of electron transport chain(Kd of 64 nM for complex III). It also is a potent mitochondrial NDH-2 inhibitorin many species.		Mitochondrial Metabolism
TN6772	Malabaricone C		Others
	Malabaricone C is a bioactive chemical.		Others
T14140	Agaric acid	Agaricinic Acid	Mitochondrial Metabolism , AChR
	Agaricic acid is an adenine nucleotide translocase antagonist.It is obtained from various plants of the fungous tribe, i.e. Polyporus officinalis and Polyporus igniarius. Agaric acid (Agaricinic Acid) induces mitochondri...		Mitochondrial Metabolism , AChR
T8091	Trans-4-Hydroxycyclohexanecarboxylic Acid		Others
	trans-4-Hydroxycyclohexanecarboxylic Acid is an organic intermediate.		Others
T7922	Kresoxim-Methyl		Others , Mitochondrial Metabolism , Antifungal
	Kresoxim-methyl is a strobilurin fungicide,inhibits conidial germination of V. inaequalis isolates from apple orchards .		Others , Mitochondrial Metabolism , Antifungal
T3804	Neomangiferin	Mangiferin 7-glucoside	Phosphatase
	Neomangiferin (Mangiferin 7-glucoside) has beneficial effects on high fat diet-induced nonalcoholic fatty liver disease in rats. Neomangiferin and mangiferin inhibit tartrate-resistant acid phosphatase, a biochemical mar...		Phosphatase
T0938	Thiabendazole	2-(4-Thiazolyl)benzimidazole	Microtubule Associated , Mitochondrial Metabolism , Parasite
	Thiabendazole (2-(4-Thiazolyl)benzimidazole) is a benzimidazole derivative with anthelminthic property.
T13795	Nicotinamide riboside		Sirtuin
	Nicotinamide riboside increases NAD[+] levels and activates SIRT1 and SIRT3, culminating in enhanced oxidative metabolism and protection against high fat diet-induced metabolic abnormalities.		Sirtuin
T4766	3-Methylglutaric acid		Endogenous Metabolite
	Methylglutaric acid is a leucine metabolite. A large amount of methylglutaric acid is identified in urine of patients with deficiency of 3-methylglutaconyl coenzyme A hydratase (PMID 6181239 ). Methylglutaric acid is als...		Endogenous Metabolite
T2970	Rotenone	Rotenon,Paraderil,Barbasco,Rotocide,Dactinol	Apoptosis , Dehydrogenase , Mitochondrial Metabolism , p53 , Autophagy
	Rotenone (Rotocide) is a natural product and a botanical insecticide. Rotenone is a mitochondrial electron transport complex I inhibitor that promotes the production of reactive oxygen species in mitochondria and induces...
TN1362	Afzelin	Kaempferol-3-O-rhamnoside	PTEN , p38 MAPK , TNF , Mitochondrial Metabolism , Antibacterial , Prostaglandin Receptor , Autophagy
	Afzelin (Kaempferol-3-O-rhamnoside) has several cellular activities such as DNA-protective, antibacterial, antioxidant, and anti-inflammatory as well as UV-absorbing activity and may protect human skin from UVB-induced d...
T0846	L-Carnitine	L(-)-Carnitine,Levocarnitine	Endogenous Metabolite , Fatty Acid Synthase
	L-Carnitine (L(-)-Carnitine) is an amino acid derivative. L-Carnitine facilitates long-chain fatty acid entry into mitochondria, delivering substrate for oxidation and subsequent energy production. Fatty acids are utiliz...		Endogenous Metabolite , Fatty Acid Synthase
T5645	Nerol	Cis-Geraniol,Neryl alcohol	Apoptosis , Reactive Oxygen Species , Mitochondrial Metabolism , Endogenous Metabolite , Antifungal
	Nerol (Neryl alcohol) is a monoterpene found in many essential oils, such as lemon balm and hop.Nerol can lessened the severity of ouabain-triggered arrhythmias in mammalian heart.
T2899	Liquiritin	Liquiritigenin-4'-O-glucoside,Liquiritoside	Reactive Oxygen Species
	Liquiritin (Liquiritigenin-4'-O-glucoside) (LIQ) is a main component among the licorice flavonoids, and possesses anti-inflammatory and anti-cancer abilities.		Reactive Oxygen Species
T0437	Inosine	INO 495,NSC 20262	ROS , Endogenous Metabolite , Adenosine Receptor
	Inosine (NSC-20262) is a purine nucleoside that has hypoxanthine linked by the N9 nitrogen to the C1 carbon of ribose. It has immunomodulatory, neuroprotective, and analgesic properties.		ROS , Endogenous Metabolite , Adenosine Receptor
T20089	ATP	Atipi,ATP disodium salt hydrate,Triphosphoric acid adenosine ester,Ara-ATP,Triphosphaden,Adenosine triphosphate;Ara-ATP,Adenosine triphosphate	Endogenous Metabolite
	ATP (Adenosine triphosphate) provides cellular energy, participates in overall energy balance, and maintains intracellular homeostasis. ATP can act as an extracellular signaling molecule through interactions with specifi...		Endogenous Metabolite
T3898	Schaftoside	APIGENIN-6-GLUCOSIDE-8-ARABINOSIDE,Shaftoside	Dynamin , Antioxidant , TLR , MyD88 , Mitochondrial Metabolism , Autophagy
	Schaftoside (APIGENIN-6-GLUCOSIDE-8-ARABINOSIDE) has antioxidant and anticancer activity.
T6220	Nicotinamide riboside chloride		Sirtuin , Endogenous Metabolite
	Nicotinamide riboside chloride, also known as NR and SRT647, is a pyridine-nucleoside form of vitamin B3 that functions as a precursor to nicotinamide adenine dinucleotide or NAD+.		Sirtuin , Endogenous Metabolite
T9352	Hydrocotarnine		Others
	hydrocotarnine is an inhibitor of Cbl.		Others
T2A2532	L-Histidine	Glyoxaline-5-alanine,L-(-)-Histidine,histidine,L-Hisidine	Mitochondrial Metabolism , Endogenous Metabolite
	L-Histidine (L-(-)-Histidine) is a semi-essential amino acid (children should obtain it from food) needed in humans for growth and tissue repair, L-Histidine is important for maintenance of myelin sheaths that protect ne...		Mitochondrial Metabolism , Endogenous Metabolite
T2901	Daidzin	NPI-031D,Daidzein 7-O-glucoside,Daidzoside,Daidzein 7-glucoside	Dehydrogenase , Reverse Transcriptase , Mitochondrial Metabolism
	Daidzin (Daidzoside) is an isoflavone isolated from soya bean with anti-oxidant, anti-carcinogenic, and anti-atherosclerotic activities.
TN1353	N-Benzyllinoleamide	(9Z,12Z)-N-Benzyloctadeca-9,12-dienamide	Others
	N-Benzyllinoleamide ((9Z,12Z)-N-Benzyloctadeca-9,12-dienamide) is a natural product isolated from Lepidium meyenii Walp, has pharmaceutical property against exercise-induced fatigue.		Others
T0700	Ursodeoxycholic acid	UDCA,Ursodiol	Potassium Channel , Endogenous Metabolite
	Ursodeoxycholic acid (UDCA) can be used to dissolve gallstones and reduce cholesterol absorption.		Potassium Channel , Endogenous Metabolite
T1153	Trimethoprim	NIH 204,BW 56-72,NSC-106568	DHFR , DNA/RNA Synthesis , Antifolate , Antibacterial , Antibiotic
	Trimethoprim (NSC-106568) is a Dihydrofolate Reductase Inhibitor Antibacterial. The mechanism of action of trimethoprim is as a Dihydrofolate Reductase Inhibitor, and Cytochrome P450 2C8 Inhibitor, and Organic Cation Tra...
T2812	ATP disodium salt hydrate	ATP disodium,ATP disodium salt,Adenosine disodium triphosphate	Others , Endogenous Metabolite
	ATP disodium salt hydrate (Adenosine disodium triphosphate) is a nucleoside triphosphate used in cells as a coenzyme often called the "molecular unit of currency" of intracellular energy transfer.		Others , Endogenous Metabolite
T9368	3,4-(Methylenedioxy)cinnamic acid	3-(Benzo[d][1,3]dioxol-5-yl)acrylic acid	Others
	3,4-(Methylenedioxy)cinnamic acid (3-(Benzo[d][1,3]dioxol-5-yl)acrylic acid) is a plant-derived compound first extracted from roots of Asparagus officinalis and further characterized as an allelochemical.		Others
T22235	Lipoic acid	R-(+)-Thioctic acid,(R)-(+)-1,2-Dithiolane-3-pentanoic acid,(R)-(+)-α-Lipoic acid	Reactive Oxygen Species , Mitochondrial Metabolism , Endogenous Metabolite
	Lipoic acid (R-(+)-Thioctic acid) is an organosulfur compound derived from octanoic acid. It is made in animals normally, and is essential for aerobic metabolism.
T5564	Tricarballylic acid	β-Carboxyglutaric acid,1,2,3-Propanetricarboxylic acid,Carballylic acid,Propane-1,2,3-tricarboxylic acid	aconitase , Mitochondrial Metabolism
	Tricarballylic acid (Carballylic acid) is an inhibitor of aconitase.		aconitase , Mitochondrial Metabolism
T1352	ATP disodium salt	Adenosine 5'-triphosphate disodium salt,ATP,ATP disodium,Adetide,Adenosine-Triphosphate,Disodium adenosine triphosphate	P2X Receptor , Endogenous Metabolite
	ATP disodium salt (Adenosine-Triphosphate) is a P2 purinoceptor agonist.		P2X Receptor , Endogenous Metabolite
T0200	α-Lipoic Acid	Thioctic acid,DL-α-Lipoic acid,(±)-α-Lipoic acid	Apoptosis , NF-κB , HIV Protease , Mitochondrial Metabolism , Endogenous Metabolite
	α-Lipoic Acid (DL-α-Lipoic acid) an octanoic acid bridged with two sulfurs so that it is sometimes also called a pentanoic acid in some naming schemes. It is biosynthesized by cleavage of LINOLEIC ACID and is a coenzyme ...
T29078	Ursodeoxycholic acid sodium	UDCA Na,UDCA sodium,Sodium Ursodeoxycholate,Ursodiol sodium,Ursodeoxycholic Acid (sodium salt),Ursodeoxycholate sodium	FXR , Endogenous Metabolite , GPCR19
	Ursodeoxycholic acid sodium (Sodium Ursodeoxycholate) is a naturally occurring secondary bile acid with anti-inflammatory and cytoprotective activities. Ursodeoxycholic acid sodium acts as signaling molecule, exerting it...		FXR , Endogenous Metabolite , GPCR19
T5213	Acetyl phosphate(lithium potassium)	Lithium potassium acetyl phosphate,Acetylphosphoric acid	Others , Endogenous Metabolite
	Acetyl phosphate lithium potassium (Lithium potassium acetyl phosphate) is a compound involved in taurine and hypotaurine metabolism as well as pyruvate metabolism. Acetyl phosphate lithium potassiu is generated from sul...		Others , Endogenous Metabolite
T4942	Galactose 1-phosphate Potassium salt	α-D-Galactose-1-phosphate Dipotassium Pentahydrate	Others , Endogenous Metabolite
	Galactose 1-phosphate Potassium salt (α-D-Galactose-1-phosphate Dipotassium Pentahydrate) is an intermediate in the galactose metabolism and nucleotide sugars metabolism pathways.		Others , Endogenous Metabolite
TN6752	Dimethyl sulfone		Endogenous Metabolite
	Dimethyl sulfone exists in all living organisms, ranging from bacteria to humans. It derives from dietary sources, from intestinal bacterial metabolism and from human endogenous methanethiol metabolism. Dimethyl sulfone ...		Endogenous Metabolite
T5078	Orotic acid monohydrate	2,4-dioxo-1H-pyrimidine-6-carboxylic acid hydrate,Orotic Acid Monohydrate,2,6-Dioxo-1,2,3,6-tetrahydropyrimidine-4-carboxylic acid hydrate	Others , Endogenous Metabolite
	Orotic acid monohydrate is an intermediate product in pyrimidine metabolism.		Others , Endogenous Metabolite
T1040	Vitamin B12	Cyanocobalamin,Cobalamin	Endogenous Metabolite
	Cyanocobalamin is a cobalt-containing coordination compound generated by intestinal microbes and a natural water-soluble vitamin of the B-complex family that must combine with Intrinsic Factor for absorption by the intes...		Endogenous Metabolite
TN7132	4,12-Dimethoxy-6-(7,8-dihydroxy-7,8-dihydrostyryl)-2-pyrone		Others
	4,12-Dimethoxy-6-(7,8-dihydroxy-7,8-dihydrostyryl)-2-pyrone is a microbial metabolism of yangonin, a major styryl lactone from Piper methysticum.		Others
T4829	3-Hydroxyphenylacetic acid		Others , Endogenous Metabolite
	3-Hydroxyphenylacetic acid is a rutin metabolite and an antioxidant. It has a protective biological activity in human. It is a substrate of enzyme 4-hydroxyphenylacetate 3-monooxygenase [EC 1.14.13.3] in the pathway tyro...		Others , Endogenous Metabolite
T5251	Phenylpyruvic acid	2-Oxo-3-phenylpropanoic acid,3-Phenylpyruvic acid	Others , Endogenous Metabolite
	Phenylpyruvic acid (3-Phenylpyruvic acid) is a keto-acid that is an intermediate or catabolic byproduct of phenylalanine metabolism. It has a slight honey-like odor. Levels of phenylpyruvate are normally very low in bloo...		Others , Endogenous Metabolite
T10943	D-(-)-Lactic acid	(R)-2-Hydroxypropionic acid	Others , Endogenous Metabolite
	D-(-)-Lactic acid is a normal intermediate in sugar fermentation (oxidation, metabolism). It is identified as a competitive inhibitor of ProDH (proline dehydrogenase) in plants.		Others , Endogenous Metabolite
T21367	Tetrahydrofolic acid	5,6,7,8-tetrahydrofolic acid,folate-H4,Tetrahydropteroylglutamic acid,th-folate	Endogenous Metabolite
	Tetrahydrofolic acid (5,6,7,8-tetrahydrofolic acid) is a vitamin B9 derivative that is a common one-carbon donor in organisms and is involved in growth and metabolism.		Endogenous Metabolite
T14840	Butyrylcarnitine		Endogenous Metabolite
	Butyrylcarnitine is a plasma metabolite that is an indicator of abnormal metabolism due to disease and is used in the diagnosis of heart failure and pancreatic cysts.		Endogenous Metabolite
T10147	4-Hydroxymephenytoin	(+/-)-4'-Hydroxymephenytoin	Others , Drug Metabolite
	4-Hydroxymephenytoin ((+/-)-4'-Hydroxymephenytoin) is the metabolism of an antiepileptic drug mephenytoin. Mephenytoin is used as a CYP2C19 substrate.		Others , Drug Metabolite
T0894	Thiamine hydrochloride	Vitamin B1,Vitamin B1 hydrochloride,Thiamine HCl,Thiamine chloride hydrochloride	Apoptosis , HBV , Endogenous Metabolite
	Thiamine hydrochloride (Vitamin B1) is the hydrochloride salt form of thiamine, a vitamin essential for aerobic metabolism, cell growth, transmission of nerve impulses and acetylcholine synthesis. Upon hydrolysis, Thiami...		Apoptosis , HBV , Endogenous Metabolite
T0800	Danthron	Dantron,1,8-Dihydroxyanthraquinone,Chrysazin,Antrapurol	Virus Protease , Antibacterial , AMPK , Autophagy
	Danthron (Antrapurol) is a natural product, regulates glucose, and lipid metabolism by activating AMPK.		Virus Protease , Antibacterial , AMPK , Autophagy
T64980	ATP disodium trihydrate	Adenosine-5'-triphosphate disodium trihydrate	Endogenous Metabolite
	ATP disodium trihydrate (Adenosine-5'-triphosphate disodium trihydrate) is an important substance for energy storage and metabolism in the body. It is an important endogenous signaling molecule in immunity and inflammati...		Endogenous Metabolite
T19115	3,4-Dimethylbenzoic acid	1-Carboxy-3,4-dimethylbenzene	Others
	3,4-Dimethylbenzoic acid (1-Carboxy-3,4-dimethylbenzene) is a product of dimethylbenzoate metabolism by Rhodococcus rhodochrous N75.		Others
T19125	3-Phenylbutyric acid		Others , Endogenous Metabolite
	3-Phenylbutyric acid undergoes metabolism through initial oxidation processes involving both its benzene ring and side chain. It serves as an effective agent for the isolation of Rhodococcus rhodochrous PB1 from compost ...		Others , Endogenous Metabolite
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天然物製品

Dihydrorotenone

TN1586

Synonym:

Target: Apoptosis, Mitochondrial Metabolism

Coenzyme A

T10857

Synonym:

Target: Endogenous Metabolite

HQNO

T8433

Synonym:

Target: Mitochondrial Metabolism

Synonym: Agaricinic Acid

Target: Mitochondrial Metabolism, AChR

trans-4-Hydroxycyclohexanecarboxylic Acid

Target: Others, Mitochondrial Metabolism, Antifungal

Neomangiferin

T3804

Synonym: Mangiferin 7-glucoside

Target: Phosphatase

Thiabendazole

T0938

Synonym: 2-(4-Thiazolyl)benzimidazole

Target: Microtubule Associated, Mitochondrial Metabolism, Parasite

Nicotinamide riboside

T13795

Synonym:

Target: Sirtuin

3-Methylglutaric acid

T4766

Synonym:

Target: Endogenous Metabolite

Rotenone

T2970

Synonym: Rotenon,Paraderil,Barbasco,Rotocide,Dactinol

Target: Apoptosis, Dehydrogenase, Mitochondrial Metabolism, p53, Autophagy

Afzelin

TN1362

Synonym: Kaempferol-3-O-rhamnoside

Target: PTEN, p38 MAPK, TNF, Mitochondrial Metabolism, Antibacterial, Prostaglandin Receptor, Autophagy

L-Carnitine

T0846

Synonym: L(-)-Carnitine,Levocarnitine

Target: Endogenous Metabolite, Fatty Acid Synthase

Nerol

T5645

Synonym: Cis-Geraniol,Neryl alcohol

Target: Apoptosis, Reactive Oxygen Species, Mitochondrial Metabolism, Endogenous Metabolite, Antifungal

Liquiritin

T2899

Synonym: Liquiritigenin-4'-O-glucoside,Liquiritoside

Target: Reactive Oxygen Species

Inosine

T0437

Synonym: INO 495,NSC 20262

Target: ROS, Endogenous Metabolite, Adenosine Receptor

ATP

T20089

Synonym: Atipi,ATP disodium salt hydrate,Triphosphoric acid adenosine ester,Ara-ATP,Triphosphaden,Adenosine triphosphate;Ara-ATP,Adenosine triphosphate

Target: Endogenous Metabolite

Schaftoside

T3898

Synonym: APIGENIN-6-GLUCOSIDE-8-ARABINOSIDE,Shaftoside

Target: Dynamin, Antioxidant, TLR, MyD88, Mitochondrial Metabolism, Autophagy

Nicotinamide riboside chloride

T6220

Synonym:

Target: Sirtuin, Endogenous Metabolite

Synonym: Glyoxaline-5-alanine,L-(-)-Histidine,histidine,L-Hisidine

Target: Mitochondrial Metabolism, Endogenous Metabolite

Daidzin

T2901

Synonym: NPI-031D,Daidzein 7-O-glucoside,Daidzoside,Daidzein 7-glucoside

Target: Dehydrogenase, Reverse Transcriptase, Mitochondrial Metabolism

N-Benzyllinoleamide

TN1353

Synonym: (9Z,12Z)-N-Benzyloctadeca-9,12-dienamide

Target: Others

Ursodeoxycholic acid

T0700

Synonym: UDCA,Ursodiol

Target: Potassium Channel, Endogenous Metabolite

Trimethoprim

T1153

Synonym: NIH 204,BW 56-72,NSC-106568

Target: DHFR, DNA/RNA Synthesis, Antifolate, Antibacterial, Antibiotic

ATP disodium salt hydrate

T2812

Synonym: ATP disodium,ATP disodium salt,Adenosine disodium triphosphate

Target: Others, Endogenous Metabolite

3,4-(Methylenedioxy)cinnamic acid

T9368

Synonym: 3-(Benzo[d][1,3]dioxol-5-yl)acrylic acid

Target: Others

Lipoic acid

T22235

Synonym: R-(+)-Thioctic acid,(R)-(+)-1,2-Dithiolane-3-pentanoic acid,(R)-(+)-α-Lipoic acid

Target: Reactive Oxygen Species, Mitochondrial Metabolism, Endogenous Metabolite

Tricarballylic acid

T5564

Synonym: β-Carboxyglutaric acid,1,2,3-Propanetricarboxylic acid,Carballylic acid,Propane-1,2,3-tricarboxylic acid

Target: aconitase, Mitochondrial Metabolism

ATP disodium salt

T1352

Synonym: Adenosine 5'-triphosphate disodium salt,ATP,ATP disodium,Adetide,Adenosine-Triphosphate,Disodium adenosine triphosphate

Target: P2X Receptor, Endogenous Metabolite

α-Lipoic Acid

T0200

Synonym: Thioctic acid,DL-α-Lipoic acid,(±)-α-Lipoic acid

Target: Apoptosis, NF-κB, HIV Protease, Mitochondrial Metabolism, Endogenous Metabolite

Ursodeoxycholic acid sodium

T29078

Synonym: UDCA Na,UDCA sodium,Sodium Ursodeoxycholate,Ursodiol sodium,Ursodeoxycholic Acid (sodium salt),Ursodeoxycholate sodium

Target: FXR, Endogenous Metabolite, GPCR19

Acetyl phosphate(lithium potassium)

T5213

Synonym: Lithium potassium acetyl phosphate,Acetylphosphoric acid

Target: Others, Endogenous Metabolite

Galactose 1-phosphate Potassium salt

T4942

Synonym: α-D-Galactose-1-phosphate Dipotassium Pentahydrate

Target: Others, Endogenous Metabolite

Dimethyl sulfone

TN6752

Synonym:

Target: Endogenous Metabolite

Orotic acid monohydrate

T5078

Synonym: 2,4-dioxo-1H-pyrimidine-6-carboxylic acid hydrate,Orotic Acid Monohydrate,2,6-Dioxo-1,2,3,6-tetrahydropyrimidine-4-carboxylic acid hydrate

Target: Others, Endogenous Metabolite

Vitamin B12

T1040

Synonym: Cyanocobalamin,Cobalamin

Target: Endogenous Metabolite

4,12-Dimethoxy-6-(7,8-dihydroxy-7,8-dihydrostyryl)-2-pyrone

TN7132

Synonym:

Target: Others

3-Hydroxyphenylacetic acid

T4829

Synonym:

Target: Others, Endogenous Metabolite

Phenylpyruvic acid

T5251

Synonym: 2-Oxo-3-phenylpropanoic acid,3-Phenylpyruvic acid

Target: Others, Endogenous Metabolite

D-(-)-Lactic acid

T10943

Synonym: (R)-2-Hydroxypropionic acid

Target: Others, Endogenous Metabolite

Tetrahydrofolic acid

T21367

Synonym: 5,6,7,8-tetrahydrofolic acid,folate-H4,Tetrahydropteroylglutamic acid,th-folate

Target: Endogenous Metabolite

Butyrylcarnitine

T14840

Synonym:

Target: Endogenous Metabolite

4-Hydroxymephenytoin

T10147

Synonym: (+/-)-4'-Hydroxymephenytoin

Target: Others, Drug Metabolite

Thiamine hydrochloride

T0894

Synonym: Vitamin B1,Vitamin B1 hydrochloride,Thiamine HCl,Thiamine chloride hydrochloride

Target: Apoptosis, HBV, Endogenous Metabolite

Danthron

T0800

Synonym: Dantron,1,8-Dihydroxyanthraquinone,Chrysazin,Antrapurol

Target: Virus Protease, Antibacterial, AMPK, Autophagy

ATP disodium trihydrate

T64980

Synonym: Adenosine-5'-triphosphate disodium trihydrate

Target: Endogenous Metabolite

3,4-Dimethylbenzoic acid

T19115

Synonym: 1-Carboxy-3,4-dimethylbenzene

Target: Others, Endogenous Metabolite

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Recombinant Proteins

Species：

Expression System：

Tag：

カタログ番号	製品名	Species	Expression System
TMPY-00322	DEC-205 Protein, Human, Recombinant (His)	Human	HEK293 Cells
	LY75 (Lymphocyte Antigen 75) is a Protein Coding gene. It is broadly expressed in the lymph node, appendix, and other tissues. LY75 knockdown in SKOV3 cells resulted in predominant upregulation of functional pathways imp...
TMPY-00395	Insulin Protein, Human, Recombinant	Human	P. pastoris (Yeast)
	INS (Insulin) is a Protein Coding gene. This gene encodes insulin, a peptide hormone that plays a vital role in the regulation of carbohydrate and lipid metabolism. After removal of the precursor signal peptide, proinsul...
TMPY-02707	PAH Protein, Human, Recombinant (415 Asn/Asp, His)	Human	Baculovirus Insect Cells
	PAH (phenylalanine hydroxylase), also known as PH, belongs to the biopterin-dependent aromatic amino acid hydroxylase family. It contains 1 ACT domain, N-terminal region of PAH is thought to contain allosteric binding si...
TMPY-02062	SULT1A1 Protein, Human, Recombinant (His)	Human	E. coli
	Sulfate conjugation catalyzed by cytosolic sulfotransferase (SULT) enzymes. The SULTs are Phase II drug-metabolizing enzymes that catalyze the addition of a sulfuryl moiety to both endogenous compounds, including steroid...
TMPY-04552	AKT1 Protein, Human, Recombinant (His)	Human	Baculovirus Insect Cells
	v-akt murine thymoma viral oncogene homolog 1 (AKT1), or protein kinase B-alpha (PKB-ALPHA) is a serine-threonine protein kinase, belonging to the Protein Kinase Superfamily. AKT1 is a major mediator of the responses to ...
TMPY-02219	Influenza A H1N1 (A/Puerto Rico/8/34/Mount Sinai) Non-structural/NS1 Protein (His)	H1N1	E. coli
	The NS1 Influenza protein is created by the internal protein-encoding, linear negative-sense, single-stranded RNA, NS gene segment and which also codes for the nuclear export protein or NEP, formerly referred to as the N...
TMPY-00481	AKR1C4 Protein, Human, Recombinant (His)	Human	E. coli
	Aldo-keto reductases comprise of AKR1C1-AKR1C4, four enzymes that catalyze NADPH dependent reductions and have been implicated in biosynthesis, intermediary metabolism, and detoxification. there is a strong correlation ...
TMPJ-01072	GALK2 Protein, Human, Recombinant (His)	Human	HEK293 Cells
	GALK2 acts as a galactokinase when galactose is present at high concentrations. GALK2 may be involved in a salvage pathway for the reutilization of free GalNAc derived from the degradation of complex carbohydrates. GALK2...
TMPH-01563	IAPP Protein, Human, Recombinant (His)	Human	P. pastoris (Yeast)
	Selectively inhibits insulin-stimulated glucose utilization and glycogen deposition in muscle, while not affecting adipocyte glucose metabolism.
TMPJ-00158	Apolipoprotein A-I/APOA1 Protein, Human, Recombinant	Human	E. coli
	Apolipoprotein A1 (APOA1) is a secreted protein which belongs to the Apolipoprotein A1/A4/E family. APOA1 is the major protein component of high density lipoprotein (HDL) in plasma. APOA1 plays a critical role in various...
TMPK-00516	BST1 Protein, Cynomolgus, Recombinant (His)	Cynomolgus	HEK293 Cells
	BST1 overexpression conferred resistance to sphingosine in yeast. BST1 deletion produced sensitivity to exogenous D-erythro-sphingosine and phytosphingosine and intracellular accumulation of sphingosine 1-phosphate upon ...
TMPH-01670	Metallothionein-4/MT4 Protein, Human, Recombinant (His & SUMO)	Human	E. coli
	Seems to bind zinc and copper. Could play a special role in regulating zinc metabolism during the differentiation of stratified epithelia.
TMPH-00608	Dihydrofolate reductase Protein, E. coli, Recombinant (His)	E. coli	E. coli
	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis.
TMPH-02562	CES1C Protein, Mouse, Recombinant (His & Myc)	Mouse	HEK293 Cells
	Involved in the detoxification of xenobiotics and in the activation of ester and amide prodrugs. Involved in the extracellular metabolism of lung surfactant.
TMPK-01087	Apolipoprotein A-V/APOA5 Protein, Mouse, Recombinant (His)	Mouse	E. coli
	APOA5 is probably the gene with the strongest effect on triglyceride (TG) metabolism. APOA5 is almost exclusively expressed in the liver, and its product apoAV has a very low circulating concentration. New physiological ...
TMPY-02622	Aldolase B Protein, Human, Recombinant (GST)	Human	E. coli
	The aldolase family members involved in metabolism and glycolysis are present in three isoforms: ALDOA, ALDOB, and ALDOC. Aldolases are differentially expressed in human tissues, and aberrant expression has been observed...
TMPH-02561	CES1C Protein, Mouse, Recombinant (GST)	Mouse	E. coli
	Involved in the detoxification of xenobiotics and in the activation of ester and amide prodrugs. Involved in the extracellular metabolism of lung surfactant.
TMPJ-01296	SULT4A1 Protein, Human, Recombinant	Human	E. coli
	Sulfotransferase 4A1 (ST4A1) is a member of the Sulfotransferase 1 family. ST4A1 is highly expressed in the cerebral cortex and frontal lobe, but no expression is detected in the pancreas. ST4A1 is a brain-specific sulfo...
TMPH-03387	TSHB Protein, Rat, Recombinant (His & Myc)	Rat	P. pastoris (Yeast)
	Indispensable for the control of thyroid structure and metabolism. TSHB Protein, Rat, Recombinant (His & Myc) is expressed in yeast with N-6xHis and C-Myc tag. The predicted molecular weight is 16.4 kDa and the accession...
TMPH-01360	GALT Protein, Human, Recombinant (His & SUMO)	Human	E. coli
	Plays an important role in galactose metabolism. GALT Protein, Human, Recombinant (His & SUMO) is expressed in E. coli expression system with N-6xHis-SUMO tag. The predicted molecular weight is 59.4 kDa and the accession...
TMPH-02618	CYP2E1 Protein, Mouse, Recombinant (His)	Mouse	E. coli
	A cytochrome P450 monooxygenase involved in the metabolism of fatty acids. Mechanistically, uses molecular oxygen inserting one oxygen atom into a substrate, and reducing the second into a water molecule, with two electr...
TMPH-02526	Arginase-2/ARG2 Protein, Mouse, Recombinant (His & SUMO)	Mouse	E. coli
	May play a role in the regulation of extra-urea cycle arginine metabolism and also in down-regulation of nitric oxide synthesis. Extrahepatic arginase functions to regulate L-arginine bioavailability to nitric oxid synth...
TMPH-00615	RecF Protein, E. coli, Recombinant (His & SUMO)	E. coli	E. coli
	The RecF protein is involved in DNA metabolism; it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP.
TMPK-00101	IL-6 Protein, Cynomolgus, Recombinant (His)	Cynomolgus	HEK293 Cells
	IL-6 (Interleukin-6) is a pleiotropic cytokine that acts in the acute phase reaction, inflammation, hematopoiesis, bone metabolism, and cancer progression.Interleukin 6 has been shown to interact with interleukin-6 recep...
TMPH-01562	IAPP Protein, Human, Recombinant (GST)	Human	E. coli
	Selectively inhibits insulin-stimulated glucose utilization and glycogen deposition in muscle, while not affecting adipocyte glucose metabolism. IAPP Protein, Human, Recombinant (GST) is expressed in E. coli expression s...
TMPY-04771	CARKL Protein, Human, Recombinant (His & GST)	Human	Baculovirus Insect Cells
	CARKL, also known as SHPK, is a nonprotein kinase of glucose metabolism. CARKL has weak homology to several carbohydrate kinases, a class of proteins involved in the phosphorylation of sugars as they enter a cell, inhibi...
TMPH-00198	Bet v 3 Protein, Betula pendula, Recombinant (His & Myc & SUMO)	Betula pendula	E. coli
	Could be involved in calcium metabolism in pollen. Binds 3 calcium ions. Bet v 3 Protein, Betula pendula, Recombinant (His & Myc & SUMO) is expressed in E. coli expression system with N-10xHis-SUMO and C-Myc tag. The pre...
TMPH-02563	CES1C Protein, Mouse, Recombinant	Mouse	E. coli
	Involved in the detoxification of xenobiotics and in the activation of ester and amide prodrugs. Involved in the extracellular metabolism of lung surfactant. CES1C Protein, Mouse, Recombinant is expressed in E. coli expr...
TMPH-02685	GPHB5 Protein, Mouse, Recombinant (His & Myc)	Mouse	E. coli
	Functions as a heterodimeric glycoprotein hormone with GPHA2 able to bind and activate the thyroid-stimulating hormone receptor (TSHR), leading to increased cAMP production. Plays a central role in controlling thyroid ce...
TMPH-03386	TSHB Protein, Rat, Recombinant (E. coli, His & Myc)	Rat	E. coli
	Indispensable for the control of thyroid structure and metabolism. TSHB Protein, Rat, Recombinant (E. coli, His & Myc) is expressed in E. coli expression system with N-10xHis and C-Myc tag. The predicted molecular weight...
TMPH-01224	Dihydrofolate reductase Protein, Human, Recombinant (His)	Human	E. coli
	Key enzyme in folate metabolism. Contributes to the de novo mitochondrial thymidylate biosynthesis pathway. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis. Binds...
TMPY-02288	Glyoxalase II/HAGH Protein, Human, Recombinant (His)	Human	E. coli
	HAGH (Hydroxyacylglutathione Hydrolase) is a Protein Coding gene. 3 alternative splicing and alternative initiation of human isoforms have been reported. The enzyme encoded by this gene is classified as a thioesterase an...
TMPH-03535	Dihydrofolate reductase Protein, S. aureus, Recombinant (His & Myc)	Staphylococcus aureus	E. coli
	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis. Dihydrofolate reductase Protein, S. aureus, Recombinant (His & Myc) is expressed...
TMPK-00050	Leptin Protein, Mouse, Recombinant (hFc)	Mouse	HEK293 Cells
	Leptin has key roles in the regulation of energy balance, body weight, metabolism, and endocrine function. Leptin levels are undetectable or very low in patients with lipodystrophy, hypothalamic amenorrhea, and congenita...
TMPH-01859	PISD Protein, Human, Recombinant (His & SUMO)	Human	E. coli
	Catalyzes the formation of phosphatidylethanolamine (PtdEtn) from phosphatidylserine (PtdSer). Plays a central role in phospholipid metabolism and in the interorganelle trafficking of phosphatidylserine. PISD Protein, Hu...
TMPH-03581	Dihydrofolate reductase Protein, S. epidermidis, Recombinant (His)	Staphylococcus epidermidis	E. coli
	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis. Dihydrofolate reductase Protein, S. epidermidis, Recombinant (His) is expressed ...
TMPH-03021	PstP Protein, Mycobacterium tuberculosis, Recombinant (His)	Mycobacterium tuberculosis	E. coli
	Plays an important role in regulating cell division and growth by reversible phosphorylation signaling. May play important roles in regulating cellular metabolism and signaling pathways, which could mediate the growth an...
TMPH-03293	FGF-23 Protein, Rat, Recombinant (E. coli, His)	Rat	E. coli
	Regulator of phosphate homeostasis. Inhibits renal tubular phosphate transport by reducing SLC34A1 levels. Regulator of vitamin-D metabolism. Negatively regulates osteoblasts differentiation and matrix mineralization. Ac...
TMPH-00911	GPT Protein, Human, Recombinant (His)	Human	E. coli
	Catalyzes the reversible transamination between alanine and 2-oxoglutarate to form pyruvate and glutamate. Participates in cellular nitrogen metabolism and also in liver gluconeogenesis starting with precursors transport...
TMPH-01094	CELA2A Protein, Human, Recombinant (His)	Human	P. pastoris (Yeast)
	Elastase that enhances insulin signaling and might have a physiologic role in cellular glucose metabolism. Circulates in plasma and reduces platelet hyperactivation, triggers both insulin secretion and degradation, and i...
TMPH-01087	CSH2 Protein, Human, Recombinant (GST & His)	Human	E. coli
	Produced only during pregnancy and is involved in stimulating lactation, fetal growth and metabolism. Does not interact with GHR but only activates PRLR through zinc-induced dimerization. CSH2 Protein, Human, Recombinant...
TMPY-01217	ANGPTL5 Protein, Human, Recombinant (GST)	Human	Baculovirus Insect Cells
	The angiopoietins are protein growth factors that promote angiogenesis, the formation of blood vessels from pre-existing blood vessels. There are now four identified angiopoietins: Ang1, Ang2, Ang3, Ang4. In addition, th...
TMPH-02582	CELA2A Protein, Mouse, Recombinant (His)	Mouse	E. coli
	Elastase that enhances insulin signaling and might have a physiologic role in cellular glucose metabolism. Circulates in plasma and reduces platelet hyperactivation, triggers both insulin secretion and degradation, and i...
TMPJ-01302	ACAT2 Protein, Human, Recombinant (His)	Human	E. coli
	ACAT2 is a cytoplasmic enzyme which belongs to the thiolase family. ACAT2 takes part in lipid metabolism, lipoprotein assembly, catalyzing cholesterol esterification in mammalian cells. It is responsible for the synthesi...
TMPH-02684	GPHB5 Protein, Mouse, Recombinant (His)	Mouse	P. pastoris (Yeast)
	Functions as a heterodimeric glycoprotein hormone with GPHA2 able to bind and activate the thyroid-stimulating hormone receptor (TSHR), leading to increased cAMP production. Plays a central role in controlling thyroid ce...
TMPH-03503	Adenylate kinase Protein, Shigella flexneri, Recombinant (His & Myc & SUMO)	Shigella flexneri	E. coli
	Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism. Adenylate kinase Protein, Shigella flexn...
TMPY-05099	GBA/glucocerebrosidase Protein, Human, Recombinant (His)	Human	HEK293 Cells
	Mutations in the GBA gene, encoding the lysosomal hydrolase glucocerebrosidase (GCase), are the most common known genetic risk factor for Parkinson's disease (PD) and dementia with Lewy bodies (DLB). ASAH1 (acid ceramida...
TMPJ-01248	Cytoglobin/CYGB Protein, Human, Recombinant (His)	Human	E. coli
	Cytoglobin is a ubiquitously globin protein that belongs to the globin family. The highest expressed in heart, stomach, bladder and small intestine. CYGB acts a protector under conditions of oxidative stress. CYGB may be...
TMPK-00764	Apolipoprotein A-II/APOA2 Protein, Human, Recombinant (hFc)	Human	HEK293 Cells
	APOA2 is a protein implicated in triglyceride, fatty acid and glucose metabolism. In pigs, the APOA2 gene is located on pig chromosome 4 (SSC4) in a QTL region affecting fatty acid composition, fatness and growth traits....
TMPK-00795	Apolipoprotein A-II/APOA2 Protein, Mouse, Recombinant (hFc)	Mouse	HEK293 Cells
	APOA2 is a protein implicated in triglyceride, fatty acid and glucose metabolism. In pigs, the APOA2 gene is located on pig chromosome 4 (SSC4) in a QTL region affecting fatty acid composition, fatness and growth traits....
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DEC-205 Protein, Human, Recombinant (His)

TMPY-00322

Species: Human

Expression System: HEK293 Cells

Insulin Protein, Human, Recombinant

TMPY-00395

Species: Human

Expression System: P. pastoris (Yeast)

PAH Protein, Human, Recombinant (415 Asn/Asp, His)

TMPY-02707

Species: Human

Expression System: Baculovirus Insect Cells

SULT1A1 Protein, Human, Recombinant (His)

TMPY-02062

Species: Human

Expression System: E. coli

AKT1 Protein, Human, Recombinant (His)

TMPY-04552

Species: Human

Expression System: Baculovirus Insect Cells

Influenza A H1N1 (A/Puerto Rico/8/34/Mount Sinai) Non-structural/NS1 Protein (His)

TMPY-02219

Species: H1N1

Expression System: E. coli

AKR1C4 Protein, Human, Recombinant (His)

TMPY-00481

Species: Human

Expression System: E. coli

GALK2 Protein, Human, Recombinant (His)

TMPJ-01072

Species: Human

Expression System: HEK293 Cells

IAPP Protein, Human, Recombinant (His)

TMPH-01563

Species: Human

Expression System: P. pastoris (Yeast)

Apolipoprotein A-I/APOA1 Protein, Human, Recombinant

TMPJ-00158

Species: Human

Expression System: E. coli

BST1 Protein, Cynomolgus, Recombinant (His)

TMPK-00516

Species: Cynomolgus

Expression System: HEK293 Cells

Metallothionein-4/MT4 Protein, Human, Recombinant (His & SUMO)

TMPH-01670

Species: Human

Expression System: E. coli

Dihydrofolate reductase Protein, E. coli, Recombinant (His)

TMPH-00608

Species: E. coli

Expression System: E. coli

CES1C Protein, Mouse, Recombinant (His & Myc)

TMPH-02562

Species: Mouse

Expression System: HEK293 Cells

Apolipoprotein A-V/APOA5 Protein, Mouse, Recombinant (His)

TMPK-01087

Species: Mouse

Expression System: E. coli

Aldolase B Protein, Human, Recombinant (GST)

TMPY-02622

Species: Human

Expression System: E. coli

CES1C Protein, Mouse, Recombinant (GST)

TMPH-02561

Species: Mouse

Expression System: E. coli

SULT4A1 Protein, Human, Recombinant

TMPJ-01296

Species: Human

Expression System: E. coli

TSHB Protein, Rat, Recombinant (His & Myc)

TMPH-03387

Species: Rat

Expression System: P. pastoris (Yeast)

GALT Protein, Human, Recombinant (His & SUMO)

TMPH-01360

Species: Human

Expression System: E. coli

CYP2E1 Protein, Mouse, Recombinant (His)

TMPH-02618

Species: Mouse

Expression System: E. coli

Arginase-2/ARG2 Protein, Mouse, Recombinant (His & SUMO)

TMPH-02526

Species: Mouse

Expression System: E. coli

RecF Protein, E. coli, Recombinant (His & SUMO)

TMPH-00615

Species: E. coli

Expression System: E. coli

IL-6 Protein, Cynomolgus, Recombinant (His)

TMPK-00101

Species: Cynomolgus

Expression System: HEK293 Cells

IAPP Protein, Human, Recombinant (GST)

TMPH-01562

Species: Human

Expression System: E. coli

CARKL Protein, Human, Recombinant (His & GST)

TMPY-04771

Species: Human

Expression System: Baculovirus Insect Cells

Bet v 3 Protein, Betula pendula, Recombinant (His & Myc & SUMO)

TMPH-00198

Species: Betula pendula

Expression System: E. coli

CES1C Protein, Mouse, Recombinant

TMPH-02563

Species: Mouse

Expression System: E. coli

GPHB5 Protein, Mouse, Recombinant (His & Myc)

TMPH-02685

Species: Mouse

Expression System: E. coli

TSHB Protein, Rat, Recombinant (E. coli, His & Myc)

TMPH-03386

Species: Rat

Expression System: E. coli

Dihydrofolate reductase Protein, Human, Recombinant (His)

TMPH-01224

Species: Human

Expression System: E. coli

Glyoxalase II/HAGH Protein, Human, Recombinant (His)

TMPY-02288

Species: Human

Expression System: E. coli

Dihydrofolate reductase Protein, S. aureus, Recombinant (His & Myc)

TMPH-03535

Species: Staphylococcus aureus

Expression System: E. coli

Leptin Protein, Mouse, Recombinant (hFc)

TMPK-00050

Species: Mouse

Expression System: HEK293 Cells

PISD Protein, Human, Recombinant (His & SUMO)

TMPH-01859

Species: Human

Expression System: E. coli

Dihydrofolate reductase Protein, S. epidermidis, Recombinant (His)

TMPH-03581

Species: Staphylococcus epidermidis

Expression System: E. coli

PstP Protein, Mycobacterium tuberculosis, Recombinant (His)

TMPH-03021

Species: Mycobacterium tuberculosis

Expression System: E. coli

FGF-23 Protein, Rat, Recombinant (E. coli, His)

TMPH-03293

Species: Rat

Expression System: E. coli

GPT Protein, Human, Recombinant (His)

TMPH-00911

Species: Human

Expression System: E. coli

CELA2A Protein, Human, Recombinant (His)

TMPH-01094

Species: Human

Expression System: P. pastoris (Yeast)

CSH2 Protein, Human, Recombinant (GST & His)

TMPH-01087

Species: Human

Expression System: E. coli

ANGPTL5 Protein, Human, Recombinant (GST)

TMPY-01217

Species: Human

Expression System: Baculovirus Insect Cells

CELA2A Protein, Mouse, Recombinant (His)

TMPH-02582

Species: Mouse

Expression System: E. coli

ACAT2 Protein, Human, Recombinant (His)

TMPJ-01302

Species: Human

Expression System: E. coli

GPHB5 Protein, Mouse, Recombinant (His)

TMPH-02684

Species: Mouse

Expression System: P. pastoris (Yeast)

Adenylate kinase Protein, Shigella flexneri, Recombinant (His & Myc & SUMO)

TMPH-03503

Species: Shigella flexneri

Expression System: E. coli

GBA/glucocerebrosidase Protein, Human, Recombinant (His)

TMPY-05099

Species: Human

Expression System: HEK293 Cells

Cytoglobin/CYGB Protein, Human, Recombinant (His)

TMPJ-01248

Species: Human

Expression System: E. coli

Apolipoprotein A-II/APOA2 Protein, Human, Recombinant (hFc)

TMPK-00764

Species: Human

Expression System: HEK293 Cells

Apolipoprotein A-II/APOA2 Protein, Mouse, Recombinant (hFc)

TMPK-00795

Species: Mouse

Expression System: HEK293 Cells

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カタログ番号	製品名
L2130	Anti-Cancer Metabolism Compound Library	1268 compounds
	A unique collection of 1268 cancer cellular metabolism related compounds for cancer research and high throughput screening (HTS) and high content screening (HCS);
L2510	Lipid Metabolism Compound Library	492 compounds
	A unique collection of 492 compounds targeting lipid metabolism, can be used for high-throughput screening (HTS) and high-content screening (HCS).
L2550	Glutamine Metabolism Compound Library	565 compounds
	A unique collection of 565 glutamine metabolism related compounds can be used for high throughput screening (HTS) and high content screening (HCS), and also is an effective tool for research in glutamine metabolism and ...
L5200	Anti-Metabolism Disease Compound Library	1544 compounds
	A unique collection of 1544 metabolism diseases related compounds for high throughput screening (HTS) and high content screening (HCS);
L2560	Metabolism Compound Library	2320 compounds

L2520	Glycometabolism Compound Library	702 compounds
	702 glycometabolism-related comounds, can be used for HTS and HCT;
L2501	Human Endogenous Metabolite Compound Library Plus	1283 compounds

L2100	Anti-Cancer Compound Library	7234 compounds
	A unique collection of 7234 compounds with anti-cancer activity for high throughput screening (HTS) and high content screening (HCS);
L1510	Nuclear Receptor Compound Library	531 compounds
	A unique collection of 531 nuclear receptor signaling targeted compounds for high throughput and high content screening;
L2540	Gut Microbial Metabolite Library	607 compounds
	A unique collection of 607 gut microbial metabolites which can be used for HTS and HCS;
L2400	Endocrinology-Hormone Compound Library	784 compounds
	A unique collection of 784 compounds targeting endocrine system for high throughput screening (HTS) and high content screening (HCS) for new drugs;
L2160	Anti-Cancer Active Compound Library	3188 compounds
	A unique collection of 3188 compounds with known anti-cancer activity for high throughput screening (HTS) and high content screening (HCS);
L1610	FDA-Approved Kinase Inhibitor Library	263 compounds
	A unique collection of 263 kinase inhibitors/regulators for specific targeting of kinases, ready for high-throughput screening and high-content screening.
L2150	Anti-Cancer Drug Library	3080 compounds
	A unique collection of 3080 anticancer drugs for high throughput screening (HTS) and high content screening (HCS);
L6130	Terpene Natural Product Library	516 compounds
	A unique collection of 516 natural terpenes and terpenoids can be used for high throughput and high content screening；
L2120	Anti-Cancer Clinical Compound Library	2545 compounds
	A unique collection of 2545 anti-cancer compounds for high throughput screening (HTS) and high content screening (HCS);
L1120	AMPK-Targeted Compound Library	80 compounds
	80 well-chosen unique AMPK-targeted small molecules；
L2110	Anti-Cancer Approved Drug Library	1779 compounds
	A unique collection of 1779 approved anti-cancer drugs for high throughput screening (HTS) and high content screening (HCS);
L2180	Anti-Cancer Compound Library Plus	1468 compounds
	Well-chosen 1468 anti-tumor compounds with unique structures;
L5300	Mitochondria-Targeted Compound Library	812 compounds
	A unique collection of 812 promising or approved mitochondria-targeted compounds including Idebenone, the only approved drug targeting mitochondria, for research in mitochondrial medicine;
L6120	Flavonoid Natural Product Library	514 compounds
	A unique collection of 514 flavonoids can be used for high throughput and high content screening；
L7100	Anti-Obesity Compound Library	2247 compounds
	A unique collection of 2247 anti-obesity compounds for high throughput and high content screening;
L8500	HIF-1 Signaling Pathway Compound Library	1336 compounds
	A unique collection of 1336 HIF-1 related small chemicals can be used for drug discovery in ischemic disease and cancer and related mechanism studies；