Powder: -20°C for 3 years | In solvent: -80°C for 1 year
TAK-071 is a potent, novel and highly selective modulator of muscarinic acetylcholine receptor 1 (M1R) positive allosteric(EC50 : 520 nM).
説明 | TAK-071 is a potent, novel and highly selective modulator of muscarinic acetylcholine receptor 1 (M1R) positive allosteric(EC50 : 520 nM). |
ターゲット&IC50 | M1R:520 nM (EC50) |
In vivo | In rats, TAK-071(0.3 mg/kg) increase hippocampal inositol monophosphate production through M1R activation and improved DB00747 -induced cognitive deficits, TAK-071(10 mg/kg) also induce diarrhea . |
分子量 | 421.46 |
分子式 | C24H24FN3O3 |
CAS No. | 1820812-16-5 |
Powder: -20°C for 3 years | In solvent: -80°C for 1 year
DMSO: 134 mg/mL(317.94 mM)
You can also refer to dose conversion for different animals. 詳細
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TAK-071 1820812-16-5 Neuroscience AChR mAChR inhibit Muscarinic acetylcholine receptor TAK 071 TAK071 Inhibitor inhibitor