Powder: -20°C for 3 years | In solvent: -80°C for 1 year
CAY10526 (BTH) is a selective mPGES-1 inhibitor that acts as an inhibitor of the NF-κB signaling pathway.
パッケージサイズ | 在庫状況 | 単価(税別) | |||
---|---|---|---|---|---|
サンプルについてお問い合わせ | |||||
1 mg | 在庫あり | ¥ 13,000 | |||
5 mg | 在庫あり | ¥ 32,000 | |||
10 mg | 在庫あり | ¥ 57,000 | |||
25 mg | 在庫あり | ¥ 123,500 | |||
50 mg | 在庫あり | ¥ 178,500 | |||
1 mL * 10 mM (in DMSO) | 在庫あり | ¥ 35,500 |
説明 | CAY10526 (BTH) is a selective mPGES-1 inhibitor that acts as an inhibitor of the NF-κB signaling pathway. |
ターゲット&IC50 | mPGES-1:1.8 μM |
In vitro | CAY10526 dose-dependently inhibits PGE2 production in lipopolysaccharide-stimulated RAW 264.7 cells with an IC50 value of 1.8 μM without any effect on COX-2 expression[1]. |
別名 | CAY-10526, BTH, CAY 10526 |
分子量 | 311.15 |
分子式 | C12H7BrO3S |
CAS No. | 938069-71-7 |
Powder: -20°C for 3 years | In solvent: -80°C for 1 year
DMSO: 16 mg/mL(51.43 mM)
DMF: 16 mg/mL(51.43 mM)
Ethanol: 1 mg/ml(3.21 mM)
You can also refer to dose conversion for different animals. 詳細
bottom
Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc.
CAY10526 938069-71-7 GPCR/G Protein Immunology/Inflammation Prostaglandin Receptor WM793 CAY-10526 PGE2 production Inhibitor inhibit SB2 microsomal PGE2 synthase-1 BTH A375 cleaved caspase 3 increases apoptosis increases BAX and BAK pro-apoptotic anti-apoptotic melanoma xenografts mPGES1 inhibitor PGE synthase CAY 10526 Prostaglandin E synthase inhibitor