Powder: -20°C for 3 years | In solvent: -80°C for 1 year
Talibegron hydrochloride (ZD2079 hydrochloride) is an β3 adrenergic receptor agonist with a pD2 of 3.72 on phenylephrine-preconstricted rat mesenteric artery. Relaxes rat mesenteric artery and isolated aorta in vitro. Inhibits ob gene expression and circulating leptin levels in lean mice in vivo.
パッケージサイズ | 在庫状況 | 単価(税別) | |||
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1 mg | 在庫あり | ¥ 11,500 | |||
5 mg | 在庫あり | ¥ 25,000 | |||
10 mg | 在庫あり | ¥ 31,000 | |||
25 mg | 在庫あり | ¥ 68,500 | |||
50 mg | 在庫あり | ¥ 99,500 | |||
100 mg | 在庫あり | ¥ 136,000 | |||
500 mg | 在庫あり | ¥ 271,000 |
説明 | Talibegron hydrochloride (ZD2079 hydrochloride) is an β3 adrenergic receptor agonist with a pD2 of 3.72 on phenylephrine-preconstricted rat mesenteric artery. Relaxes rat mesenteric artery and isolated aorta in vitro. Inhibits ob gene expression and circulating leptin levels in lean mice in vivo. |
In vitro | Talibegron hydrochloride ( 0.01-1000 μM) produces a concentration-dependent relaxation of phenylephrine-preconstricted isolated mesenteric arteries and causes full relaxation with 1 mM[1]. |
In vivo | The β3-adrenoceptor agonist talibegron hydrochloride produced a concentration-dependent relaxation of phenylephrine-preconstricted isolated mesenteric arteries. The shape of the concentration–response curve of talibegron hydrochloride also suggests that this drug, which was studied up to 1 mm, causes full relaxation [3]. |
別名 | ZD2079 hydrochloride, ZD 2079 |
分子量 | 351.83 |
分子式 | C18H22ClNO4 |
CAS No. | 178600-17-4 |
Powder: -20°C for 3 years | In solvent: -80°C for 1 year
H2O: < 8.8 mg/mL
DMSO: 50 mg/mL (142.11 mM)
You can also refer to dose conversion for different animals. 詳細
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Talibegron hydrochloride 178600-17-4 GPCR/G Protein Neuroscience Adrenergic Receptor Talibegron Hydrochloride ZD2079 hydrochloride ZD2079 ZD2079 Hydrochloride ZD 2079 ZD-2079 Hydrochloride ZD 2079 Hydrochloride ZD-2079 Inhibitor inhibitor inhibit