Powder: -20°C for 3 years | In solvent: -80°C for 1 year
Tiagabine hydrochloride (NO050328 hydrochloride) is the hydrochloride salt form of tiagabine, a nipecotic acid derivative with anticonvulsant property. A selective gamma-aminobutyric acid (GABA) reuptake inhibitor.
パッケージサイズ | 在庫状況 | 単価(税別) | |||
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10 mg | 在庫あり | ¥ 11,500 | |||
25 mg | 在庫あり | ¥ 14,500 | |||
50 mg | 在庫あり | ¥ 26,000 | |||
100 mg | 在庫あり | ¥ 46,500 | |||
200 mg | 在庫あり | ¥ 76,000 | |||
1 mL * 10 mM (in DMSO) | 在庫あり | ¥ 11,000 |
説明 | Tiagabine hydrochloride (NO050328 hydrochloride) is the hydrochloride salt form of tiagabine, a nipecotic acid derivative with anticonvulsant property. A selective gamma-aminobutyric acid (GABA) reuptake inhibitor. |
In vitro | Tiagabine is a potent inhibitor of GABA uptake into neurons and glial cells. It is involved in modulating GABA levels, especially in areas such as the hippocampus and thalamus[2]. Tiagabine not only affected the decay kinetics of the IPSCs, it also reduced the frequency of occurrence of both spontaneous and miniature IPSCs[4]. |
In vivo | Tiagabine offers a significant neuroprotection in global ischemia in gerbils when given 30 min before ischemia but not when given 3 h after ischemia[3]. |
別名 | NO328 hydrochloride, NO050328 hydrochloride, TGB hydrochloride, Gabitril, Gabitril hydrochloride |
分子量 | 412.01 |
分子式 | C20H25NO2S2·HCl |
CAS No. | 145821-59-6 |
Powder: -20°C for 3 years | In solvent: -80°C for 1 year
DMSO: 41.2 mg/mL (100 mM)
H2O: 20.6 mg/mL (50 mM)
You can also refer to dose conversion for different animals. 詳細
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Tiagabine hydrochloride 145821-59-6 Membrane transporter/Ion channel Neuroscience GABA Receptor NO050328 TGB NO-050328 Hydrochloride NO328 hydrochloride NO-050328 γ-Aminobutyric acid Receptor NO 050328 NO050328 Hydrochloride TGB Hydrochloride NO 328 Hydrochloride inhibit Tiagabine Hydrochloride NO-328 Hydrochloride NO328 Hydrochloride NO-328 Gabitril Hydrochloride NO 050328 Hydrochloride NO328 NO050328 hydrochloride TGB hydrochloride Gamma-aminobutyric acid Receptor Gabitril Tiagabine NO 328 Gabitril hydrochloride Inhibitor inhibitor