Powder: -20°C for 3 years | In solvent: -80°C for 1 year
Vatanidipine (AE0047) is a novel dihydropyridine (DHP)-type calcium channel blocker with slow-onset pharmacological actions.A slow-onset and long-lasting hypotensive action was observed in various experimental hypertensive models.
パッケージサイズ | 在庫状況 | 単価(税別) |
---|---|---|
1 mg | 在庫あり | ¥ 75,500 |
5 mg | 在庫あり | ¥ 183,500 |
10 mg | 在庫あり | ¥ 250,500 |
25 mg | 在庫あり | ¥ 379,000 |
50 mg | 在庫あり | ¥ 512,000 |
100 mg | 在庫あり | ¥ 672,500 |
1 mL * 10 mM (in DMSO) | 在庫あり | ¥ 294,000 |
説明 | Vatanidipine (AE0047) is a novel dihydropyridine (DHP)-type calcium channel blocker with slow-onset pharmacological actions.A slow-onset and long-lasting hypotensive action was observed in various experimental hypertensive models. |
In vivo | Vatanidipine (AE0047 ) (10 and 50 ng/kg/min) was administered intrarenally, increases in the basal renal blood flow and urine formation were observed. During Vatanidipine (50 ng/kg/min) infusion, low-frequency RNS-induced antidiuretic action and increase in NESR were markedly attenuated. In addition, high-frequency RNS-induced renal vasoconstriction was significantly suppressed by Vatanidipineinfusion at higher doses. Lower doses of Vatanidipine (10 ng/kg/min) tended to attenuate the low- and high-frequency RNS-induced antidiuretic actions, although neither of the RNS-induced increases in NESR were suppressed by lower doses of Vatanidipine[2]. |
別名 | AE-0047, AE 0047, AE0047 |
分子量 | 686.8 |
分子式 | C41H42N4O6 |
CAS No. | 116308-55-5 |
Powder: -20°C for 3 years | In solvent: -80°C for 1 year
DMSO: 27.5 mg/mL (40.04 mM)
You can also refer to dose conversion for different animals. 詳細
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Vatanidipine 116308-55-5 Membrane transporter/Ion channel Metabolism Calcium Channel AE-0047 AE 0047 AE0047 Inhibitor inhibitor inhibit