Powder: -20°C for 3 years | In solvent: -80°C for 1 year
AChE/BChE/MAO-B-IN-1 is a reversible, non-time-dependent inhibitor of AChE, BChE and MAO-B that crosses the blood-brain barrier and exhibits inhibitory effects on hAChE, hBChE and hMAO-B with IC50s of 7.31, 0.56 and 26.1 μM, respectively. 1 had a neuroprotective effect and was not significantly cytotoxic.
説明 | AChE/BChE/MAO-B-IN-1 is a reversible, non-time-dependent inhibitor of AChE, BChE and MAO-B that crosses the blood-brain barrier and exhibits inhibitory effects on hAChE, hBChE and hMAO-B with IC50s of 7.31, 0.56 and 26.1 μM, respectively. 1 had a neuroprotective effect and was not significantly cytotoxic. |
ターゲット&IC50 | AChE:7.31 μM, BChE:0.56 μM, MAO-B:26.1 μM |
In vitro | AChE/BChE/MAO-B-IN-1 inhibits neuronal cell death induced by amyloid β 1-42 (Aβ 1-42).[1] |
分子量 | 324.42 |
分子式 | C20H24N2O2 |
CAS No. | 2416910-82-0 |
Powder: -20°C for 3 years | In solvent: -80°C for 1 year
DMSO: 27.5 mg/mL (84.77 mM)
You can also refer to dose conversion for different animals. 詳細
bottom
Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc.
AChE/BChE/MAO-B-IN-1 2416910-82-0 Metabolism Neuroscience MAO AChE Inhibitor inhibitor inhibit