Powder: -20°C for 3 years | In solvent: -80°C for 1 year
BSJ-04-122 is a covalent MKK4/7 dual inhibitor that inhibits MKK4 and MKK7 with IC50 values of 4 nM and 181 nM, respectively.BSJ-04-122 can be used for cancer research.
パッケージサイズ | 在庫状況 | 単価(税別) | |||
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サンプルについてお問い合わせ | |||||
1 mg | 在庫あり | ¥ 8,000 | |||
5 mg | 在庫あり | ¥ 17,500 | |||
10 mg | 在庫あり | ¥ 27,500 | |||
25 mg | 在庫あり | ¥ 55,500 | |||
50 mg | 在庫あり | ¥ 89,500 | |||
100 mg | 在庫あり | ¥ 143,000 |
説明 | BSJ-04-122 is a covalent MKK4/7 dual inhibitor that inhibits MKK4 and MKK7 with IC50 values of 4 nM and 181 nM, respectively.BSJ-04-122 can be used for cancer research. |
ターゲット&IC50 | MKK4:4 nM, MKK7:181 nM |
In vitro |
BSJ-04-122 has inhibitory activity against MKK4 and MKK7 with IC50 values of 4 nM and 181 nM respectively.[1] BSJ-04-122 (1, 5, 10 μM; 6 h) induces a strong reduction in JNK phosphorylation.[1] BSJ-04-122 (0, 1.25, 2.5, 5, 10, 20 μM; 72 h) showed enhanced antiproliferative effects when combined with JNK-IN-8.[1] |
分子量 | 313.74 |
分子式 | C15H12ClN5O |
CAS No. | 2513289-74-0 |
Powder: -20°C for 3 years | In solvent: -80°C for 1 year
DMSO: 16.6 mg/mL(53.1 mM), Sonication is recommended.
You can also refer to dose conversion for different animals. 詳細
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BSJ-04-122 2513289-74-0 MAPK JNK Inhibitor inhibitor inhibit