Powder: -20°C for 3 years | In solvent: -80°C for 1 year
CDK9-IN-15 is a potent small molecule CDK9 inhibitor, which can block the phosphorylation of positive transcription elongation factor b (P-TEFb) on the C-terminal region of RNA Poly-II by degradation and inhibition of CDK9, inhibit transcription, and rapidly reduce the level of intracellular mRNA, thereby causing apoptosis of tumor cells.
説明 | CDK9-IN-15 is a potent small molecule CDK9 inhibitor, which can block the phosphorylation of positive transcription elongation factor b (P-TEFb) on the C-terminal region of RNA Poly-II by degradation and inhibition of CDK9, inhibit transcription, and rapidly reduce the level of intracellular mRNA, thereby causing apoptosis of tumor cells. |
分子量 | 293.34 |
分子式 | C16H11N3OS |
CAS No. | 852678-17-2 |
Powder: -20°C for 3 years | In solvent: -80°C for 1 year
DMSO: 112.5 mg/mL (383.5 mM), Sonication is recommended.
You can also refer to dose conversion for different animals. 詳細
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CDK9-IN-15 852678-17-2 Cell Cycle/Checkpoint CDK Inhibitor inhibitor inhibit