Powder: -20°C for 3 years | In solvent: -80°C for 1 year
CHPG hydrochloride is a selective agonist of mGluR5.
説明 | CHPG hydrochloride is a selective agonist of mGluR5. |
In vitro | After SO2 derivatives treatment, CHPG hydrochloride (10-500 µM) increases the cell viability and reduces the release of LDH. CHPG hydrochloride (0.5 mM) protects BV2 cells against SO2-induced apoptosis and increases the TSG-6 expression through the TSG-6/NF-κB pathway[1]. |
In vivo | In adult Sprague-Dawley male rats, injection of CHPG hydrochloride (250 nM) reduces significantly cerebral lesion volume by activation of the ERK and Akt signaling pathways[2]. |
別名 | CHPG hydrochloride(170846-74-9 Free base) |
分子量 | 238.07 |
分子式 | C8H9Cl2NO3 |
CAS No. | T10809L |
Powder: -20°C for 3 years | In solvent: -80°C for 1 year
DMSO: 30 mg/mL (126.01 mM)
You can also refer to dose conversion for different animals. 詳細
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CHPG hydrochloride T10809L MAPK Neuroscience NF-Κb ERK NF-κB GluR CHPG Hydrochloride CHPG hydrochloride(170846-74-9 Free base) Inhibitor inhibitor inhibit