Powder: -20°C for 3 years | In solvent: -80°C for 1 year
BAY-0069 is a potent and selective PPARγ transactivator that inhibits human PPARγ and murine PPARγ with IC50s of 6.3 nM and 24 nM, respectively.BAY-0069 can be used in cancer research.
パッケージサイズ | 在庫状況 | 単価(税別) | |||
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サンプルについてお問い合わせ | |||||
1 mg | 在庫あり | ¥ 8,000 | |||
5 mg | 在庫あり | ¥ 18,500 | |||
10 mg | 在庫あり | ¥ 29,500 | |||
25 mg | 在庫あり | ¥ 66,500 | |||
50 mg | 在庫あり | ¥ 104,500 | |||
100 mg | 在庫あり | ¥ 158,500 | |||
500 mg | 在庫あり | ¥ 333,000 |
説明 | BAY-0069 is a potent and selective PPARγ transactivator that inhibits human PPARγ and murine PPARγ with IC50s of 6.3 nM and 24 nM, respectively.BAY-0069 can be used in cancer research. |
ターゲット&IC50 | PPARγ (human):6.3 nM, PPARγ (rat):24 nM, CYP2C8:4.3 μM |
In vitro | BAY-0069 (0.0001, 0.001, 0.01, 0.01 and 1 μM; 7 days) leads to antiproliferative effects in the PPARγ-amplified cell line UM-UC-9.[1] |
In vivo | BAY-0069 (1 μM; 1 h) shows excellent microsomal stability with CL(b,hmic) of 0.47 L/h/kg in human liver microsomes and CL(b,rhep) of 3.9 L/h/kg in rat liver hepatocytes.[1] |
分子量 | 466.28 |
分子式 | C22H16BrN3O4 |
CAS No. | 420826-65-9 |
Powder: -20°C for 3 years | In solvent: -80°C for 1 year
DMSO: 90.0 mg/mL (193.0 mM), Sonication and heating to 60℃ are recommended.
You can also refer to dose conversion for different animals. 詳細
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BAY-0069 420826-65-9 DNA Damage/DNA Repair Metabolism PPAR BAY0069 BAY 0069 CompoundBAY0069 Inhibitor inhibitor inhibit