Powder: -20°C for 3 years | In solvent: -80°C for 1 year
CP 96021 is a group of 5-HT1 receptors and 5-HT2 receptors antagonists that have anti-inflammatory properties and are non-non-self anti-ulcer compounds for the treatment of gastrointestinal tract and respiratory asthma.
説明 | CP 96021 is a group of 5-HT1 receptors and 5-HT2 receptors antagonists that have anti-inflammatory properties and are non-non-self anti-ulcer compounds for the treatment of gastrointestinal tract and respiratory asthma. |
ターゲット&IC50 | PAF:0.16 mg/kg(ED50), LTD4:0.46mg/kg(ED50) |
In vivo | CP-96021 inhibits iv LTD4- and iv PAF-induced bronchoconstriction in guinea pigs with ED50s of 0.46 and 0.16 mg/kg p.o. respectively. CP-96021 effectively blocks the combined airway obstructive effects of endogenously released PAF and LTD4 stimulated by aerosolized antigen challenge in guinea pigs with an ED50s of 1.8 mg/kg p.o[1] |
分子量 | 492.57 |
分子式 | C29H21FN4OS |
CAS No. | 139401-43-7 |
Powder: -20°C for 3 years | In solvent: -80°C for 1 year
DMSO: 4.93 mg/mL (10 mM), Sonication is recommended.
You can also refer to dose conversion for different animals. 詳細
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Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc.
CP 96021 139401-43-7 GPCR/G Protein Neuroscience 5-HT Receptor CP96021 CP-96021 Inhibitor inhibitor inhibit