Powder: -20°C for 3 years | In solvent: -80°C for 1 year
Dalzanemdor (SAGE-718) is an NMDA receptor-positive modulator of metabolism that can be used to study Huntington's chorea, Alzheimer's disease, and cognitive dysfunction.
パッケージサイズ | 在庫状況 | 単価(税別) | |
---|---|---|---|
1 mg | 在庫あり | ¥ 154,000 | |
5 mg | 在庫あり | ¥ 337,500 | |
25 mg | 約8-10 週間 | お問い合わせ | |
50 mg | 約8-10 週間 | お問い合わせ |
説明 | Dalzanemdor (SAGE-718) is an NMDA receptor-positive modulator of metabolism that can be used to study Huntington's chorea, Alzheimer's disease, and cognitive dysfunction. |
In vivo | SAGE-718 (Dalzanemdor) (5), a potent and high intrinsic activity NMDAR PAM with an optimized pharmacokinetic profile for oral dosing. Compound 5 has completed phase 1 single ascending dose and multiple ascending dose clinical trials and is currently undergoing phase 2 clinical trials for the treatment of cognitive impairment in Huntington's disease.[2] |
別名 | SAGE-718 |
分子量 | 456.62 |
分子式 | C27H43F3O2 |
CAS No. | 1629853-48-0 |
Powder: -20°C for 3 years | In solvent: -80°C for 1 year
chloroform: 5.68mg/mL (12.44mM), Sonication is recommended.
You can also refer to dose conversion for different animals. 詳細
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Dalzanemdor 1629853-48-0 Membrane transporter/Ion channel Neuroscience iGluR NMDAR SAGE-718 SAGE718 SAGE 718 Inhibitor inhibitor inhibit