store at low temperature
Powder: -20°C for 3 years | In solvent: -80°C for 1 year
JNJ-1289 is a selective, potent, and competitive inhibitor of human spermine oxidase (hSMOX) with an IC50 value of 50 nM.JNJ-1289 has potential anticancer and anti-inflammatory activity for the study of polyamine catabolic disorders.
パッケージサイズ | 在庫状況 | 単価(税別) |
---|---|---|
1 mg | 在庫あり | ¥ 91,500 |
5 mg | 在庫あり | ¥ 223,000 |
10 mg | 在庫あり | ¥ 271,000 |
25 mg | 在庫あり | ¥ 363,000 |
50 mg | 在庫あり | ¥ 454,500 |
100 mg | 在庫あり | ¥ 574,000 |
説明 | JNJ-1289 is a selective, potent, and competitive inhibitor of human spermine oxidase (hSMOX) with an IC50 value of 50 nM.JNJ-1289 has potential anticancer and anti-inflammatory activity for the study of polyamine catabolic disorders. |
In vitro |
In a time-dependent manner, JNJ-1289 inhibits hSMOX activity, with assessments at 0 and 2 hours[1]. Initially, JNJ-1289 forms a weak complex with hSMOX, characterized by an apparent Ki value of 1.4 μM. Subsequently, a relatively slow protein isomerization occurs, leading to the formation of the final tightly bound inhibitor-enzyme complex[1]. |
分子量 | 308.36 |
分子式 | C16H12N4OS |
CAS No. | 792898-18-1 |
store at low temperature
Powder: -20°C for 3 years | In solvent: -80°C for 1 year
DMSO: 50 mg/mL (162.15 mM)
You can also refer to dose conversion for different animals. 詳細
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JNJ-1289 792898-18-1 Stem Cells Smo Inhibitor inhibitor inhibit