Powder: -20°C for 3 years | In solvent: -80°C for 1 year
LYP-IN-3 (compound D34) is a selective Lymphoid-tyrosine phosphatase (LYP) inhibitor (Ki=0.93 μM) that modulates the T-cell receptor (TCR) signaling pathway during tumor progression. It promotes T-cell activation, hinders M2 macrophage polarization, and increases PD-1/PD-L1 expression. When combined with PD-1/PD-L1 inhibitors, LYP-IN-3 may enhance cancer immunotherapy [1].
説明 | LYP-IN-3 (compound D34) is a selective Lymphoid-tyrosine phosphatase (LYP) inhibitor (Ki=0.93 μM) that modulates the T-cell receptor (TCR) signaling pathway during tumor progression. It promotes T-cell activation, hinders M2 macrophage polarization, and increases PD-1/PD-L1 expression. When combined with PD-1/PD-L1 inhibitors, LYP-IN-3 may enhance cancer immunotherapy [1]. |
分子量 | 589.66 |
分子式 | C35H27NO6S |
Powder: -20°C for 3 years | In solvent: -80°C for 1 year
You can also refer to dose conversion for different animals. 詳細
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LYP-IN-3 Metabolism Phosphatase Inhibitor inhibitor inhibit