Powder: -20°C for 3 years | In solvent: -80°C for 1 year
mTOR inhibitor 9d is a dual inhibitor of the protein kinases mTOR and PI3K with an mTOR IC50 value of 0.31 nm, and can be used for the treatment of leukemia, skin cancer, breast cancer, lung cancer and colon cancer.
パッケージサイズ | 在庫状況 | 単価(税別) |
---|---|---|
1 mg | 在庫あり | ¥ 80,500 |
5 mg | 在庫あり | ¥ 190,000 |
10 mg | 在庫あり | ¥ 259,500 |
25 mg | 在庫あり | ¥ 365,000 |
50 mg | 在庫あり | ¥ 454,500 |
100 mg | 在庫あり | ¥ 574,000 |
500 mg | 在庫あり | ¥ 1,124,500 |
説明 | mTOR inhibitor 9d is a dual inhibitor of the protein kinases mTOR and PI3K with an mTOR IC50 value of 0.31 nm, and can be used for the treatment of leukemia, skin cancer, breast cancer, lung cancer and colon cancer. |
ターゲット&IC50 | Phosphatidylinositol 3-kinase PIK3CA:324 nM, mTOR:0.31 nM, LNCaP cells:180 nM |
In vitro | mTOR inhibitor 9d (compound 9d) inhibitory concentration against the proliferation of human prostate cancer LNCaP cell line by cellular proliferation assay with IC50 is 180 nM.[2] |
分子量 | 425.5 |
分子式 | C21H23N5O3S |
CAS No. | 1144075-38-6 |
Powder: -20°C for 3 years | In solvent: -80°C for 1 year
DMSO: 45 mg/mL (105.76 mM)
You can also refer to dose conversion for different animals. 詳細
bottom
Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc.
mTOR inhibitor 9d 1144075-38-6 PI3K/Akt/mTOR signaling PI3K mTOR 1(2hydroxyethyl)3{4[4(8oxa3azabicyclo[3.2.1]oct3yl)thieno[3,2d]pyrimidin2yl]phenyl}urea Inhibitor inhibitor inhibit