Powder: -20°C for 3 years | In solvent: -80°C for 1 year
Nampt activator-2 is a NAMPT activator (EC50: 0.023 μM). Nampt activator-2 has an affinity for CYP2C9, 2D6, and 2C19 with affinity values of 0.060 μM, 0.41 μM, and 0.59 μM, respectively.Nampt activator-2 can be used in the study of atherosclerosis, obesity, type II diabetes, insulin resistance, and type I diabetes.
パッケージサイズ | 在庫状況 | 単価(税別) | |||
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1 mg | 在庫あり | ¥ 19,500 | |||
5 mg | 在庫あり | ¥ 45,500 | |||
10 mg | 在庫あり | ¥ 75,500 | |||
25 mg | 在庫あり | ¥ 152,500 | |||
50 mg | 在庫あり | ¥ 227,500 | |||
100 mg | 在庫あり | ¥ 385,500 | |||
500 mg | 在庫あり | ¥ 778,000 |
説明 | Nampt activator-2 is a NAMPT activator (EC50: 0.023 μM). Nampt activator-2 has an affinity for CYP2C9, 2D6, and 2C19 with affinity values of 0.060 μM, 0.41 μM, and 0.59 μM, respectively.Nampt activator-2 can be used in the study of atherosclerosis, obesity, type II diabetes, insulin resistance, and type I diabetes. |
ターゲット&IC50 | NAMPT:0.023 μM(EC50) |
In vitro | Nampt activator-2 (compound 34) (10 μM; 4 h) causes a significant increase in NMN and NAD in A549 lung epithelial cells.[1] |
In vivo | Nampt activator-2 (compound 34) (1 mg/kg IV; 10 mg/kg PO; once) exhibits low plasma clearance, good exposure, and excellent oral bioavailability (%F = 80).[1] |
分子量 | 390.84 |
分子式 | C17H15ClN4O3S |
CAS No. | 2237268-90-3 |
Powder: -20°C for 3 years | In solvent: -80°C for 1 year
DMSO: 100 mg/mL (255.86 mM), Sonication is recommended.
You can also refer to dose conversion for different animals. 詳細
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Nampt activator-2 2237268-90-3 Metabolism P450 NAMPT Inhibitor inhibitor inhibit