Powder: -20°C for 3 years | In solvent: -80°C for 1 year
SIRT2-IN-9 is a selective SRIT2 inhibitor with an IC50 value of 1.3 μM.SIRT2-IN-9 inhibits the proliferation of MCF-7 breast cancer cells.SIRT2-IN-9 can be used for cancer research.
パッケージサイズ | 在庫状況 | 単価(税別) | |||
---|---|---|---|---|---|
サンプルについてお問い合わせ | |||||
5 mg | 在庫あり | ¥ 16,000 | |||
10 mg | 在庫あり | ¥ 27,000 | |||
25 mg | 在庫あり | ¥ 57,000 | |||
50 mg | 在庫あり | ¥ 90,000 | |||
100 mg | 在庫あり | ¥ 135,000 |
説明 | SIRT2-IN-9 is a selective SRIT2 inhibitor with an IC50 value of 1.3 μM.SIRT2-IN-9 inhibits the proliferation of MCF-7 breast cancer cells.SIRT2-IN-9 can be used for cancer research. |
ターゲット&IC50 | SIRT2:1.3 μM |
In vitro |
SIRT2-IN-9 (1-100 μM; 15 min) dose-dependently inhibits SRIT2 (IC50=1.3 μM), and inhibits SRIT1 and SRIT3 (IC50s>300 μM).[1] SIRT2-IN-9 (0-50 μM; 72 h) affects the cell viability of MCF-7 cells and dose-dependently inhibited cell proliferation of MCF-7 breast cancer cells.[1] SIRT2-IN-9 (0-50 μM; 6 h) affects acetylation of α-tubulin protein.[1] |
分子量 | 438.57 |
分子式 | C21H22N6OS2 |
CAS No. | 522650-91-5 |
Powder: -20°C for 3 years | In solvent: -80°C for 1 year
DMSO: 4.0 mg/mL (9.2 mM), Sonication and heating to 70℃ are recommended.
You can also refer to dose conversion for different animals. 詳細
bottom
Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc.
SIRT2-IN-9 522650-91-5 Chromatin/Epigenetic DNA Damage/DNA Repair Sirtuin Inhibitor inhibitor inhibit