Powder: -20°C for 3 years | In solvent: -80°C for 1 year
SLC26A3-IN-1 is an inhibitor of the anion-exchange protein SLC26A3 with an IC50 value of 340 nM.SLC26A3 is a solute carrier (SLC) protein and a member of the SLC26 family, which has a wide range of anionic specificities for chloride, bicarbonate, sulfate, and oxalate.SLC26A3 is downregulated in adenomas (DRA) and is involved in the intestinal absorption of chloride and oxalate and is associated with chloride-losing diarrhea. SLC26A3 is downregulated in adenomas (DRA), is involved in the intestinal absorption of chloride and oxalate, and is associated with chloride-losing diarrhea.
パッケージサイズ | 在庫状況 | 単価(税別) | |||
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1 mg | 在庫あり | ¥ 45,000 | |||
5 mg | 在庫あり | ¥ 99,000 | |||
10 mg | 在庫あり | ¥ 146,000 | |||
25 mg | 在庫あり | ¥ 226,500 | |||
50 mg | 在庫あり | ¥ 312,500 | |||
100 mg | 在庫あり | ¥ 420,000 | |||
500 mg | 在庫あり | ¥ 844,500 |
説明 | SLC26A3-IN-1 is an inhibitor of the anion-exchange protein SLC26A3 with an IC50 value of 340 nM.SLC26A3 is a solute carrier (SLC) protein and a member of the SLC26 family, which has a wide range of anionic specificities for chloride, bicarbonate, sulfate, and oxalate.SLC26A3 is downregulated in adenomas (DRA) and is involved in the intestinal absorption of chloride and oxalate and is associated with chloride-losing diarrhea. SLC26A3 is downregulated in adenomas (DRA), is involved in the intestinal absorption of chloride and oxalate, and is associated with chloride-losing diarrhea. |
ターゲット&IC50 | SLC26A3:340 Nm |
In vitro | SLC26A3-IN-1 (Compound 4a) (10 μM; 10 min) inhibitory rate on SLC26A3 is 87%.[1] |
分子量 | 358.39 |
分子式 | C23H18O4 |
CAS No. | 307552-53-0 |
Powder: -20°C for 3 years | In solvent: -80°C for 1 year
DMSO: 50 mg/mL (139.51 mM), Sonication is recommended.
You can also refer to dose conversion for different animals. 詳細
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SLC26A3-IN-1 307552-53-0 Metabolism transporter Inhibitor inhibitor inhibit