Powder: -20°C for 3 years | In solvent: -80°C for 1 year
TRK-IN-23 (compound 24b) is a potent, orally active inhibitor of TRK with IC50s of 0.5 nM for TRKA, 9 nM for TRKC, 14 nM for TRKA G595R, 4.4 nM for TRKA F589L, and 4.8 nM for TRKA G667C. It induces apoptosis in Ba/F3-TRKAG595R and Ba/F3-TRKAG667C cells [1].
パッケージサイズ | 在庫状況 | 単価(税別) |
---|---|---|
25 mg | 約6-8 週間 | ¥ 349,000 |
50 mg | 約6-8 週間 | ¥ 454,500 |
100 mg | 約6-8 週間 | ¥ 574,000 |
説明 | TRK-IN-23 (compound 24b) is a potent, orally active inhibitor of TRK with IC50s of 0.5 nM for TRKA, 9 nM for TRKC, 14 nM for TRKA G595R, 4.4 nM for TRKA F589L, and 4.8 nM for TRKA G667C. It induces apoptosis in Ba/F3-TRKAG595R and Ba/F3-TRKAG667C cells [1]. |
ターゲット&IC50 | TrkA:0.5 nM, TrkC:9 nM, TrkA G595R:14 nM, TrkA F589L:4.4 nM, TrkA G667C:4.8 nM |
分子量 | 364.37 |
分子式 | C20H17FN4O2 |
CAS No. | 2924344-29-4 |
Powder: -20°C for 3 years | In solvent: -80°C for 1 year
You can also refer to dose conversion for different animals. 詳細
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TRK-IN-23 2924344-29-4 Tyrosine Kinase/Adaptors Trk receptor Inhibitor inhibitor inhibit