Powder: -20°C for 3 years | In solvent: -80°C for 1 year
USP15-IN-1 is a potent USP15 inhibitor (IC50 is 3.76 μM). USP15-IN-1 showed high antiproliferative activity against non-small cell lung cancer and leukemia cells. USP15 is an interacting protein of cGAS, and USP15 can promote cGAS to recognize DNA and activate downstream signaling pathways.
パッケージサイズ | 在庫状況 | 単価(税別) | |||
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サンプルについてお問い合わせ | |||||
1 mg | 在庫あり | ¥ 29,500 | |||
5 mg | 在庫あり | ¥ 74,000 | |||
10 mg | 在庫あり | ¥ 117,500 | |||
25 mg | 在庫あり | ¥ 190,500 | |||
50 mg | 在庫あり | ¥ 264,000 | |||
100 mg | 在庫あり | ¥ 356,000 | |||
500 mg | 在庫あり | ¥ 682,000 |
説明 | USP15-IN-1 is a potent USP15 inhibitor (IC50 is 3.76 μM). USP15-IN-1 showed high antiproliferative activity against non-small cell lung cancer and leukemia cells. USP15 is an interacting protein of cGAS, and USP15 can promote cGAS to recognize DNA and activate downstream signaling pathways. |
ターゲット&IC50 | USP15:3.76 μM |
In vitro | USP15-IN-1 (0.001-5 μM; 48 h) demonstrates significant inhibitory effects on the proliferation of non-small cell lung carcinoma and leukemia cells, as reported in.[1] |
分子量 | 377.44 |
分子式 | C22H23N3O3 |
CAS No. | 2260826-16-0 |
Powder: -20°C for 3 years | In solvent: -80°C for 1 year
DMSO: 90.0 mg/mL (238.4 mM), Sonication is recommended.
You can also refer to dose conversion for different animals. 詳細
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USP15-IN-1 2260826-16-0 Cell Cycle/Checkpoint DNA Damage/DNA Repair Ubiquitination DUB Inhibitor inhibitor inhibit