Powder: -20°C for 3 years | In solvent: -80°C for 1 year
Wu-5 is a potent USP10 inhibitor that inhibits FLT3 and AMPK pathways, promoting the breakdown of FLT3-ITD and inducing apoptosis.
パッケージサイズ | 在庫状況 | 単価(税別) | |||
---|---|---|---|---|---|
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1 mg | 在庫あり | ¥ 17,500 | |||
5 mg | 在庫あり | ¥ 45,500 | |||
10 mg | 在庫あり | ¥ 72,000 | |||
25 mg | 在庫あり | ¥ 144,500 | |||
50 mg | 在庫あり | ¥ 229,000 | |||
100 mg | 在庫あり | ¥ 305,500 | |||
500 mg | 在庫あり | ¥ 617,500 |
説明 | Wu-5 is a potent USP10 inhibitor that inhibits FLT3 and AMPK pathways, promoting the breakdown of FLT3-ITD and inducing apoptosis. |
In vitro |
Wu-5 (10 μM; 24, 48, 72 h) selectively induces death in FLT3-ITD positive AML cells[1]. Wu-5 (1, 2.5, 5 μM; 24, 48 h) induces apoptosis in FLT3-ITD positive AML cells in a time- and concentration-dependent manner[1]. Wu-5 (5 μM; 24 h) induces degradation of FLT3-ITD through the proteasome pathway[1]. |
分子量 | 351.33 |
分子式 | C15H13NO7S |
CAS No. | 2630378-05-9 |
Powder: -20°C for 3 years | In solvent: -80°C for 1 year
DMSO: 20 mg/mL (56.93 mM), Sonication is recommended.
You can also refer to dose conversion for different animals. 詳細
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Wu-5 2630378-05-9 Cell Cycle/Checkpoint DNA Damage/DNA Repair Ubiquitination DUB Wu5 Inhibitor inhibitor inhibit