Epidermal growth factor (EGF) is a protein that stimulates cell growth and differentiation by binding to its receptor, EGFR. EGF acts by binding with high affinity to epidermal growth factor receptor (EGFR) on the cell surface. This stimulates ligand-induced dimerization, activating the intrinsic protein-tyrosine kinase activity of the receptor. The tyrosine kinase activity, in turn, initiates a signal transduction cascade that results in a variety of biochemical changes within the cell – a rise in intracellular calcium levels, increased glycolysis and protein synthesis, and increases in the expression of certain genes including the gene for EGFR – that ultimately lead to DNA synthesis and cell proliferation.
カタログ番号 | 製品名 / Synonyms | Species | Expression System |
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TMPY-03958 | TGF alpha Protein, Human, Recombinant
TGF alpha Protein, Human, Recombinant
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Human | E. coli |
The miR-137 served as a tumor suppressor in non-small cell lung cancer (NSCLC) and its suppressive effect is mediated by repressing TGFA expression. TGFA gene ex... | |||
TMPY-01560 | EGF Protein, Human, Recombinant
EGF Protein, Human, Recombinant
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Human | E. coli |
EGF is the founding member of the EGF-family of proteins. Members of this protein family have highly similar structural and functional characteristics. EGF conta... | |||
TMPY-01062 | EGF Protein, Human, Recombinant (hFc)
EGF Protein, Human, Recombinant (hFc)
|
Human | HEK293 |
EGF is the founding member of the EGF-family of proteins. Members of this protein family have highly similar structural and functional characteristics. EGF conta... | |||
TMPY-06984 | EGF Protein, Mouse, Recombinant (Yeast)
EGF Protein, Mouse, Recombinant (Yeast)
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Mouse | Yeast |
EGF is the founding member of the EGF-family of proteins. Members of this protein family have highly similar structural and functional characteristics. EGF conta... | |||
TMPY-06984 | EGF Protein, Mouse, Recombinant (Yeast)
EGF Protein, Mouse, Recombinant (Yeast)
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Mouse | Yeast |
EGF is the founding member of the EGF-family of proteins. Members of this protein family have highly similar structural and functional characteristics. EGF conta... | |||
TMPY-06984 | EGF Protein, Mouse, Recombinant (Yeast)
EGF Protein, Mouse, Recombinant (Yeast)
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Mouse | Yeast |
EGF is the founding member of the EGF-family of proteins. Members of this protein family have highly similar structural and functional characteristics. EGF conta... | |||
TMPY-06984 | EGF Protein, Mouse, Recombinant (Yeast)
EGF Protein, Mouse, Recombinant (Yeast)
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Mouse | Yeast |
EGF is the founding member of the EGF-family of proteins. Members of this protein family have highly similar structural and functional characteristics. EGF conta... | |||
TMPY-06597 | Betacellulin Protein, Rhesus, Recombinant (hFc)
Betacellulin Protein, Rhesus, Recombinant (hFc)
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Rhesus | HEK293 |
Betacellulin(BTC) is a member of the epidermal growth factor (EGF) family. These soluble proteins are ligands for one or more of the four receptor tyrosine kinas... | |||
TMPY-06493 | EGF Protein, Feline, Recombinant (hFc)
EGF Protein, Feline, Recombinant (hFc)
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Feline | HEK293 |
EGF is the founding member of the EGF-family of proteins. Members of this protein family have highly similar structural and functional characteristics. EGF conta... | |||
TMPY-05813 | Neuregulin-1/NRG1 Protein, Human, Recombinant , Biotinylated
Neuregulin-1/NRG1 Protein, Human, Recombinant , Biotinylated
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Human | HEK293 |
Neuregulin 1 or NRG1 is one of four proteins in the neuregulin family that act on the EGFR family of receptors. This growth factor was originally identified as a... | |||
TMPY-05062 | NRG2 Protein, Human, Recombinant (His)
NRG2 Protein, Human, Recombinant (His)
|
Human | HEK293 |
Neuregulin-2 (NRG2) is a novel member of the neuregulin family of growth and differentiation factors. Through interaction with the ErbB family of receptors, neur... | |||
TMPY-04884 | EGF Protein, Canine, Recombinant
EGF Protein, Canine, Recombinant
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Canine | Yeast |
EGF is the founding member of the EGF-family of proteins. Members of this protein family have highly similar structural and functional characteristics. EGF conta... | |||
TMPY-04647 | EGFL6 Protein, Human, Recombinant (His & FLAG)
EGFL6 Protein, Human, Recombinant (His & FLAG)
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Human | Baculovirus-Insect Cells |
EGFL6, also known as EGF-L6, belongs to the epidermal growth factor (EGF) repeat superfamily. Members of this superfamily are characterized by the presence of EG... | |||
TMPY-04339 | EGFL7 Protein, Human, Recombinant (His)
EGFL7 Protein, Human, Recombinant (His)
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Human | Baculovirus-Insect Cells |
Epidermal growth factor-like protein 7, also known as EGF-like protein 7, Multiple epidermal growth factor-like domains protein 7, Multiple EGF-like domains pr... | |||
TMPY-04300 | NRG3 Protein, Human, Recombinant (His)
NRG3 Protein, Human, Recombinant (His)
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Human | HEK293 |
NRG3 (Neuregulin 3) is a Protein Coding gene. NRG3 is a member of the neuregulin family of EGF proteins. It has been shown to activate the tyrosine phosphorylati... | |||
TMPY-04237 | Neuregulin-1/NRG1 Protein, Canine, Recombinant (aa 176-240, His)
Neuregulin-1/NRG1 Protein, Canine, Recombinant (aa 176-240, His)
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Canine | HEK293 |
Neuregulin 1 or NRG1 is one of four proteins in the neuregulin family that act on the EGFR family of receptors. This growth factor was originally identified as a... | |||
TMPY-04220 | EGF Protein, Rat, Recombinant
EGF Protein, Rat, Recombinant
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Rat | E. coli |
EGF is the founding member of the EGF-family of proteins. Members of this protein family have highly similar structural and functional characteristics. EGF conta... | |||
TMPY-04088 | Neuregulin-1/NRG1 Protein, Canine, Recombinant
Neuregulin-1/NRG1 Protein, Canine, Recombinant
|
Canine | HEK293 |
Neuregulin 1 or NRG1 is one of four proteins in the neuregulin family that act on the EGFR family of receptors. This growth factor was originally identified as a... | |||
TMPY-03943 | Neuregulin-1/NRG1 Protein, Canine, Recombinant (hFc)
Neuregulin-1/NRG1 Protein, Canine, Recombinant (hFc)
|
Canine | HEK293 |
Neuregulin 1 or NRG1 is one of four proteins in the neuregulin family that act on the EGFR family of receptors. This growth factor was originally identified as a... | |||
TMPY-03903 | Neuregulin-1/NRG1 Protein, Canine, Recombinant (aa 19-240, His)
Neuregulin-1/NRG1 Protein, Canine, Recombinant (aa 19-240, His)
|
Canine | HEK293 |
Neuregulin 1 or NRG1 is one of four proteins in the neuregulin family that act on the EGFR family of receptors. This growth factor was originally identified as a... |