Epidermal growth factor (EGF) is a protein that stimulates cell growth and differentiation by binding to its receptor, EGFR. EGF acts by binding with high affinity to epidermal growth factor receptor (EGFR) on the cell surface. This stimulates ligand-induced dimerization, activating the intrinsic protein-tyrosine kinase activity of the receptor. The tyrosine kinase activity, in turn, initiates a signal transduction cascade that results in a variety of biochemical changes within the cell – a rise in intracellular calcium levels, increased glycolysis and protein synthesis, and increases in the expression of certain genes including the gene for EGFR – that ultimately lead to DNA synthesis and cell proliferation.
カタログ番号 | 製品名 / Synonyms | Species | Expression System |
---|---|---|---|
TMPY-03902 | Neuregulin-1/NRG1 Protein, Canine, Recombinant (mFc)
Neuregulin-1/NRG1 Protein, Canine, Recombinant (mFc)
|
Canine | HEK293 Cells |
Neuregulin-1/NRG1 Protein, Canine, Recombinant (mFc) is expressed in HEK293 mammalian cells with mFc tag. The predicted molecular weight is 34 kDa and the access... | |||
TMPY-03780 | EGFL6 Protein, Human, Recombinant (His)
EGFL6 Protein, Human, Recombinant (His)
|
Human | Baculovirus Insect Cells |
EGFL6 Protein, Human, Recombinant (His) is expressed in Baculovirus insect cells with His tag. The predicted molecular weight is 60.5 kDa and the accession numbe... | |||
TMPY-03701 | EGF Protein, Mouse, Recombinant
EGF Protein, Mouse, Recombinant
|
Mouse | HEK293 Cells |
EGF Protein, Mouse, Recombinant is expressed in HEK293 mammalian cells. The predicted molecular weight is 6.2 kDa; 14 kDa, reducing conditions and the accession ... | |||
TMPY-03569 | Betacellulin Protein, Human, Recombinant (hFc)
Betacellulin Protein, Human, Recombinant (hFc)
|
Human | HEK293 Cells |
Betacellulin Protein, Human, Recombinant (hFc) is expressed in HEK293 mammalian cells with hFc tag. The predicted molecular weight is 36 kDa and the accession nu... | |||
TMPY-03010 | NRG1 beta 1 Protein, Human, Recombinant
NRG1 beta 1 Protein, Human, Recombinant
|
Human | HEK293 Cells |
NRG1 beta 1 Protein, Human, Recombinant is expressed in HEK293 mammalian cells. The predicted molecular weight is 26.8 kDa and the accession number is Q02297-6. | |||
TMPY-02721 | NRG1 alpha Protein, Human, Recombinant (His)
NRG1 alpha Protein, Human, Recombinant (His)
|
Human | HEK293 Cells |
NRG1 alpha Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 25.5kDa and the accession num... | |||
TMPY-02720 | NRG1 alpha Protein, Human, Recombinant (hFc)
NRG1 alpha Protein, Human, Recombinant (hFc)
|
Human | HEK293 Cells |
NRG1 alpha Protein, Human, Recombinant (hFc) is expressed in HEK293 mammalian cells with Fc tag. The predicted molecular weight is 51 kDa and the accession numbe... | |||
TMPY-02719 | NRG1 alpha Protein, Human, Recombinant (EGF Domain, hFc)
NRG1 alpha Protein, Human, Recombinant (EGF Domain, hFc)
|
Human | HEK293 Cells |
NRG1 alpha Protein, Human, Recombinant (EGF Domain, hFc) is expressed in HEK293 mammalian cells with Fc tag. The predicted molecular weight is 35.8 kDa and the a... | |||
TMPY-02708 | NRG4 Protein, Human, Recombinant
NRG4 Protein, Human, Recombinant
|
Human | E. coli |
NRG4 (neuregulin 4) is a member of the neuregulin protein family. The neuregulins consist of four structurally-related proteins that are part of the EGF family o... | |||
TMPY-02705 | NRG1 beta 1 Protein, Human, Recombinant (hFc)
NRG1 beta 1 Protein, Human, Recombinant (hFc)
|
Human | HEK293 Cells |
NRG1 beta 1 Protein, Human, Recombinant (hFc) is expressed in HEK293 mammalian cells with Fc tag. The predicted molecular weight is 55.2 kDa and the accession nu... | |||
TMPY-02600 | NRG1 beta 1 Protein, Human, Recombinant (EGF Domain, hFc)
NRG1 beta 1 Protein, Human, Recombinant (EGF Domain, hFc)
|
Human | HEK293 Cells |
NRG1 beta 1 Protein, Human, Recombinant (EGF Domain, hFc) is expressed in HEK293 mammalian cells with Fc tag. The predicted molecular weight is 36.7 kDa and the ... | |||
TMPY-02539 | EGF Protein, Canine, Recombinant (His)
EGF Protein, Canine, Recombinant (His)
|
Canine | E. coli |
EGF Protein, Canine, Recombinant (His) is expressed in E. coli expression system with His tag. The predicted molecular weight is 8.3 kDa and the accession number... | |||
TMPY-02267 | EGF Protein, Mouse, Recombinant (hFc)
EGF Protein, Mouse, Recombinant (hFc)
|
Mouse | HEK293 Cells |
EGF Protein, Mouse, Recombinant (hFc) is expressed in HEK293 mammalian cells with hFc tag. The predicted molecular weight is 34.5 kDa and the accession number is... | |||
TMPY-02178 | EGFL7 Protein, Mouse, Recombinant (His)
EGFL7 Protein, Mouse, Recombinant (His)
|
Mouse | Baculovirus Insect Cells |
EGFL7 Protein, Mouse, Recombinant (His) is expressed in Baculovirus insect cells with His tag. The predicted molecular weight is 29.8 kDa and the accession numbe... | |||
TMPY-02169 | Epiregulin Protein, Human, Recombinant (hFc)
Epiregulin Protein, Human, Recombinant (hFc)
|
Human | HEK293 Cells |
Epiregulin Protein, Human, Recombinant (hFc) is expressed in HEK293 mammalian cells with hFc tag. The predicted molecular weight is 33.8 kDa and the accession nu... | |||
TMPY-02166 | Epiregulin Protein, Mouse, Recombinant (hFc)
Epiregulin Protein, Mouse, Recombinant (hFc)
|
Mouse | HEK293 Cells |
Epiregulin Protein, Mouse, Recombinant (hFc) is expressed in HEK293 mammalian cells with hFc tag. The predicted molecular weight is 33.8 kDa and the accession nu... | |||
TMPY-01323 | Betacellulin Protein, Mouse, Recombinant (His & hFc)
Betacellulin Protein, Mouse, Recombinant (His & hFc)
|
Mouse | HEK293 Cells |
Betacellulin Protein, Mouse, Recombinant (His & hFc) is expressed in HEK293 mammalian cells with His and hFc tag. The predicted molecular weight is 38 kDa and th... | |||
TMPY-00479 | Neuregulin-1/NRG1 Protein, Human, Recombinant (hFc)
Neuregulin-1/NRG1 Protein, Human, Recombinant (hFc)
|
Human | HEK293 Cells |
Neuregulin-1/NRG1 Protein, Human, Recombinant (hFc) is expressed in HEK293 mammalian cells with hFc tag. The predicted molecular weight is 35.5 kDa and the acces... | |||
TMPY-00343 | RTN4RL1 Protein, Human, Recombinant (hFc)
RTN4RL1 Protein, Human, Recombinant (hFc)
|
Human | HEK293 Cells |
RTN4RL1 Protein, Human, Recombinant (hFc) is expressed in HEK293 mammalian cells with hFc tag. The predicted molecular weight is 71.5 kDa and the accession numbe... | |||
TMPY-00220 | EGF Protein, Mouse, Recombinant (His)
EGF Protein, Mouse, Recombinant (His)
|
Mouse | HEK293 Cells |
EGF Protein, Mouse, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 111.3 kDa and the accession number i... |