Epidermal growth factor (EGF) is a protein that stimulates cell growth and differentiation by binding to its receptor, EGFR. EGF acts by binding with high affinity to epidermal growth factor receptor (EGFR) on the cell surface. This stimulates ligand-induced dimerization, activating the intrinsic protein-tyrosine kinase activity of the receptor. The tyrosine kinase activity, in turn, initiates a signal transduction cascade that results in a variety of biochemical changes within the cell – a rise in intracellular calcium levels, increased glycolysis and protein synthesis, and increases in the expression of certain genes including the gene for EGFR – that ultimately lead to DNA synthesis and cell proliferation.
カタログ番号 | 製品名 / Synonyms | Species | Expression System |
---|---|---|---|
TMPY-03958 | TGF alpha Protein, Human, Recombinant
TGF alpha Protein, Human, Recombinant
|
Human | E. coli |
The miR-137 served as a tumor suppressor in non-small cell lung cancer (NSCLC) and its suppressive effect is mediated by repressing TGFA expression. TGFA gene ex... | |||
TMPY-01560 | EGF Protein, Human, Recombinant
EGF Protein, Human, Recombinant
|
Human | E. coli |
EGF Protein, Human, Recombinant is expressed in E. coli expression system. The predicted molecular weight is 6.35 kDa and the accession number is P01133-1. | |||
TMPY-01062 | EGF Protein, Human, Recombinant (hFc)
EGF Protein, Human, Recombinant (hFc)
|
Human | HEK293 Cells |
EGF Protein, Human, Recombinant (hFc) is expressed in HEK293 mammalian cells with hFc tag. The predicted molecular weight is 33 kDa and the accession number is P... | |||
TMPY-06984 | EGF Protein, Mouse, Recombinant (Yeast)
EGF Protein, Mouse, Recombinant (Yeast)
|
Mouse | P. pastoris (Yeast) |
EGF Protein, Mouse, Recombinant (Yeast) is expressed in yeast. The predicted molecular weight is 6 KDa. and the accession number is P01132. | |||
TMPY-06984 | EGF Protein, Mouse, Recombinant (Yeast)
EGF Protein, Mouse, Recombinant (Yeast)
|
Mouse | P. pastoris (Yeast) |
EGF Protein, Mouse, Recombinant (Yeast) is expressed in yeast. The predicted molecular weight is 6 KDa. and the accession number is P01132. | |||
TMPY-06984 | EGF Protein, Mouse, Recombinant (Yeast)
EGF Protein, Mouse, Recombinant (Yeast)
|
Mouse | P. pastoris (Yeast) |
EGF Protein, Mouse, Recombinant (Yeast) is expressed in yeast. The predicted molecular weight is 6 KDa. and the accession number is P01132. | |||
TMPY-06984 | EGF Protein, Mouse, Recombinant (Yeast)
EGF Protein, Mouse, Recombinant (Yeast)
|
Mouse | P. pastoris (Yeast) |
EGF Protein, Mouse, Recombinant (Yeast) is expressed in yeast. The predicted molecular weight is 6 KDa. and the accession number is P01132. | |||
TMPY-06597 | Betacellulin Protein, Rhesus, Recombinant (hFc)
Betacellulin Protein, Rhesus, Recombinant (hFc)
|
Rhesus | HEK293 Cells |
Betacellulin Protein, Rhesus, Recombinant (hFc) is expressed in HEK293 mammalian cells with hFc tag. The predicted molecular weight is 36 kDa and the accession n... | |||
TMPY-06493 | EGF Protein, Feline, Recombinant (hFc)
EGF Protein, Feline, Recombinant (hFc)
|
Feline | HEK293 Cells |
EGF Protein, Feline, Recombinant (hFc) is expressed in HEK293 mammalian cells with hFc tag. The predicted molecular weight is 34.63 kDa and the accession number ... | |||
TMPY-05813 | Neuregulin-1/NRG1 Protein, Human, Recombinant , Biotinylated
Neuregulin-1/NRG1 Protein, Human, Recombinant , Biotinylated
|
Human | HEK293 Cells |
Neuregulin-1/NRG1 Protein, Human, Recombinant , Biotinylated is expressed in HEK293 mammalian cells. The predicted molecular weight is 26.8 kDa and the accession... | |||
TMPY-05062 | NRG2 Protein, Human, Recombinant (His)
NRG2 Protein, Human, Recombinant (His)
|
Human | HEK293 Cells |
Neuregulin-2 (NRG2) is a novel member of the neuregulin family of growth and differentiation factors. Through interaction with the ErbB family of receptors, neur... | |||
TMPY-04884 | EGF Protein, Canine, Recombinant
EGF Protein, Canine, Recombinant
|
Canine | P. pastoris (Yeast) |
EGF Protein, Canine, Recombinant is expressed in yeast. The predicted molecular weight is 6.2 kDa and the accession number is Q9BEA0. | |||
TMPY-04647 | EGFL6 Protein, Human, Recombinant (His & FLAG)
EGFL6 Protein, Human, Recombinant (His & FLAG)
|
Human | Baculovirus Insect Cells |
EGFL6 Protein, Human, Recombinant (His & FLAG) is expressed in Baculovirus insect cells with His and Flag tag. The predicted molecular weight is 61.5 kDa and the... | |||
TMPY-04339 | EGFL7 Protein, Human, Recombinant (His)
EGFL7 Protein, Human, Recombinant (His)
|
Human | Baculovirus Insect Cells |
EGFL7 Protein, Human, Recombinant (His) is expressed in Baculovirus insect cells with His tag. The predicted molecular weight is 29.4 kDa and the accession numbe... | |||
TMPY-04300 | NRG3 Protein, Human, Recombinant (His)
NRG3 Protein, Human, Recombinant (His)
|
Human | HEK293 Cells |
NRG3 Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 8.5 kDa and the accession number is... | |||
TMPY-04237 | Neuregulin-1/NRG1 Protein, Canine, Recombinant (aa 176-240, His)
Neuregulin-1/NRG1 Protein, Canine, Recombinant (aa 176-240, His)
|
Canine | HEK293 Cells |
Neuregulin-1/NRG1 Protein, Canine, Recombinant (aa 176-240, His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 9.7 kDa. | |||
TMPY-04220 | EGF Protein, Rat, Recombinant
EGF Protein, Rat, Recombinant
|
Rat | E. coli |
EGF Protein, Rat, Recombinant is expressed in E. coli expression system. The predicted molecular weight is 6.3 kDa and the accession number is P07522. | |||
TMPY-04088 | Neuregulin-1/NRG1 Protein, Canine, Recombinant
Neuregulin-1/NRG1 Protein, Canine, Recombinant
|
Canine | HEK293 Cells |
Neuregulin-1/NRG1 Protein, Canine, Recombinant is expressed in HEK293 mammalian cells. The predicted molecular weight is 24.7 kDa and the accession number is XP_... | |||
TMPY-03943 | Neuregulin-1/NRG1 Protein, Canine, Recombinant (hFc)
Neuregulin-1/NRG1 Protein, Canine, Recombinant (hFc)
|
Canine | HEK293 Cells |
Neuregulin-1/NRG1 Protein, Canine, Recombinant (hFc) is expressed in HEK293 mammalian cells with hFc tag. The predicted molecular weight is 50.8 kDa and the acce... | |||
TMPY-03903 | Neuregulin-1/NRG1 Protein, Canine, Recombinant (aa 19-240, His)
Neuregulin-1/NRG1 Protein, Canine, Recombinant (aa 19-240, His)
|
Canine | HEK293 Cells |
Neuregulin-1/NRG1 Protein, Canine, Recombinant (aa 19-240, His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 25.5 kDa a... |