Interferons, IFNs

Interferons (IFNs) are a group of signaling proteins made and released by host cells in response to the presence of several viruses. IFNs belong to the large class of proteins known as cytokines. Interferons are named for their ability to "interfere" with viral replication by protecting cells from virus infections. Production of interferons occurs mainly in response to microbes, such as viruses and bacteria, and their products. More than twenty distinct IFN genes and proteins have been identified in animals, including humans. They are typically divided among three classes: Type I IFN, Type II IFN, and Type III IFN. All interferons share several common effects: antiviral, up-regulate major histocompatibility complex molecules, and increase immunoproteasome activity. Interferon therapy is used (in combination with chemotherapy and radiation) as a treatment for some cancers.

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カタログ番号	製品名 / Synonyms	Species	Expression System
TMPY-00829	Interferon alpha 4/IFNA4 Protein, Human, Recombinant (hFc) Interferon alpha 4/IFNA4 Protein, Human, Recombinant (hFc)	Human	HEK293 Cells
TMPY-00829	Interferon alpha 4/IFNA4 Protein, Human, Recombinant (hFc) is expressed in HEK293 mammalian cells with hFc tag. The predicted molecular weight is 46 kDa and the ...
TMPY-00527	IFN gamma Protein, Rhesus, Recombinant IFN gamma Protein, Rhesus, Recombinant	Rhesus	E. coli
TMPY-00527	IFN gamma Protein, Rhesus, Recombinant is expressed in E. coli expression system. The predicted molecular weight is 16.9 kDa and the accession number is G7N7K9.
TMPY-00454	IL-28B Protein, Mouse, Recombinant (His) IL-28B Protein, Mouse, Recombinant (His)	Mouse	HEK293 Cells
TMPY-00454	IL-28B Protein, Mouse, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 21.1 kDa and the accession number...
TMPY-00096	Interferon alpha 2/IFNA2 Protein, Rhesus, Recombinant Interferon alpha 2/IFNA2 Protein, Rhesus, Recombinant	Rhesus	P. pastoris (Yeast)
TMPY-00096	Interferon alpha 2/IFNA2 Protein, Rhesus, Recombinant is expressed in yeast. The predicted molecular weight is 19.5 kDa and the accession number is B6CK11.
TMPK-00075	IFN-alpha 1/IFNA1 Protein, Human, Recombinant (hFc) IFN-alpha 1/IFNA1 Protein, Human, Recombinant (hFc)	Human	HEK293 Cells
TMPK-00075	IFN-α, a cytokine expressed in human islets from individuals affected by type 1 diabetes, plays a key role in the pathogenesis of diabetes by upregulating inflam...
TMPK-00074	IFN-alpha 1/IFNA1 Protein, Mouse, Recombinant (hFc) IFN-alpha 1/IFNA1 Protein, Mouse, Recombinant (hFc)	Mouse	HEK293 Cells
TMPK-00074	IFN-α, a cytokine expressed in human islets from individuals affected by type 1 diabetes, plays a key role in the pathogenesis of diabetes by upregulating inflam...
TMPK-00048	IFN gamma Protein, Human, Recombinant (His & Avi), Biotinylated IFN gamma Protein, Human, Recombinant (His & Avi), Biotinylated	Human	HEK293 Cells
TMPK-00048	Interferon-gamma (IFN gamma) is a cytokine that plays physiologically important roles in promoting innate and adaptive immune responses. The absence of IFN gamma...
TMPJ-01371	Limitin Protein, Mouse, Recombinant (His) Limitin Protein, Mouse, Recombinant (His)	Mouse	HEK293 Cells
TMPJ-01371	Limitin, also called IFN-ζ, is a secreted interferon (IFN)-like glycoprotein. Limitin has approximately 30% sequence homology with IFN-α, IFN-β, and IFN-ω and bi...
TMPJ-00780	IFN-alpha 6/IFNA6 Protein, Human, Recombinant (His) IFN-alpha 6/IFNA6 Protein, Human, Recombinant (His)	Human	HEK293 Cells
TMPJ-00780	Interferon α-6 (IFN-α6) is a secreted protein which belongs to the α/β interferon family. IFN-α6 is produced by macrophages, expressed at low level, only 1.0% of...
TMPJ-00747	IFN-alpha 2/IFNA2 Protein, Mouse, Recombinant IFN-alpha 2/IFNA2 Protein, Mouse, Recombinant	Mouse	E. coli
TMPJ-00747	At least 23 different variants of Interferon-α are known. The individual proteins have molecular masses between 19-26 kD and consist of proteins with lengths of ...
TMPJ-00076	IL-28B Protein, Human, Recombinant IL-28B Protein, Human, Recombinant	Human	HEK293 Cells
TMPJ-00076	Interleukin-28B, also known as Cytokine Zcyto22, Interferon lambda-3, Interferon lambda-4, IFNL3, IFNL4, ZCYTO22 and IL28B, is a secreted cytokine which belongs ...