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カタログ番号 | 製品名 | 別名 | ターゲット |
---|---|---|---|
T8342 | BRD9876 | Others , Kinesin , Microtubule Associated | |
BRD9876 is a selective inhibitor of MM1S growth. | |||
T8572 | CL 218872 | GABA Receptor | |
CL 218872 is a benzodiazepine agonist displaying selectivity for α1 subunit-containing GABAA receptors (Ki values are 130, 1820, 1530, > 10000, 490 and > 10000 nM for α1, α2, α3, α4, α5 and α6-subunit containing receptor... | |||
T80166 | α-Conotoxin BuIA | ||
α-Conotoxin BuIA is a paralytic peptide neurotoxin that acts as a competitive antagonist of nicotinic acetylcholine receptors (nAChR), with inhibitory concentration 50 (IC50) values of 0.258 nM for α6/α3β2, 1.54 nM for α... | |||
T78125 | PVZB1194 | Kinesin | |
PVZB1194, a biphenyl-type inhibitor of Kinesin spindle protein Eg5 (KIF11), exhibits anticancer potential by inducing cell cycle arrest and apoptosis through inhibiting Eg5 ATPase activity. It binds to the α4/α6 alloster... | |||
T78827 | CVN417 | Others | |
CVN417 is an orally active antagonist of nAChR containing the α6 subunit, modulating phasic dopaminergic neurotransmission in an impulse-dependent fashion. It inhibits Ca(2+) efflux through nAChR subunits, displaying IC5... | |||
T16084 | MK-0343 | MRK-409 | Others |
MK0343 is an orally bioavailable GABAA receptor subtype-selective partial agonist and is a non-sedating anxiolytic. |