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Search Results for " 1071992-99-8 "

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カタログ番号 製品名 別名 ターゲット
T6763 Xevinapant ARRY-334543,SM-406,AT406,Debio-1143 IAP
Xevinapant (Debio-1143) is a potent Smac mimetic and an antagonist of IAP (inhibitor of apoptosis protein via E3 ubiquitin ligase), binding to XIAP-BIR3, cIAP1-BIR3 and cIAP2-BIR3 with Ki of 66.4 nM, 1.9 nM, and 5.1 nM, ...
T6719 Varlitinib ASLAN001,ARRY-334543 HER
Varlitinib (ASLAN001) is a potent, reversible, small molecule pan-EGFR inhibitor with IC50s of 7, 2, 4 nM for HER1, HER2 and HER4, respectively.
T3299 Xevinapant hydrochloride AT-406 HCl,SM-406 Apoptosis , IAP
Xevinapant hydrochloride (AT-406 HCl) , an orally active antagonist of multiple inhibitor of apoptosis proteins(IAP), inhibits progression of human ovarian Y binding to XIAP-BIR3, cIAP1-BIR3 and cIAP2-BIR3 with Ki of 66....