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TP1277 |
Bradykinin
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Endogenous Metabolite
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Bradykinin Receptor
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Bradykinin is an inflammatory mediator. It is a peptide that causes blood vessels to dilate (enlarge) via the release of prostacyclin, nitric oxide, and Endothelium-Derived Hyperpolarizing Factor. Bradykinin is a physiol... |
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TP1181 |
Bradykinin (2-9)
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Des-Arg1-bradykinin |
Bradykinin Receptor
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Bradykinin (2-9) (Des-Arg1-bradykinin) is an amino-truncated peptide compound that is a metabolite of Bradykinin. It is formed by the cleavage action of Aminopeptidase P. |
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T36442L |
(Hyp³)-Bradykinin acetate
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(Hyp³)-Bradykinin acetate (37642-65-2 Free base) |
Bradykinin Receptor
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(Hyp³)-Bradykinin acetate is an agonist of bradykinin B2 receptor and stimulates inositol phosphate production in cultured human fibroblasts. |
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TP1918L |
Lys-[Des-Arg9]Bradykinin,TFA
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Lys-[Des-Arg9]Bradykinin,TFA 71800-36-7(fb-tfa) |
Bradykinin Receptor
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Lys-[Des-Arg9]Bradykinin,TFA is Endogenous potent and highly selective bradykinin B1 receptor agonist (Ki values are 0.12 and > 30000 nM at human B1 and B2 receptors respectively). Hypotensive agent that reduces peripher... |
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TP1918L1 |
Lys-[Des-Arg9]Bradykinin acetate
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Lys-[Des-Arg9]Bradykinin acetate (71800-36-7 free base) |
Bradykinin Receptor
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Lys-[Des-Arg9]Bradykinin acetate is an endogenous potent and highly selective bradykinin B1 receptor agonist (Ki values are 0.12 and > 30000 nM at human B1 and B2 receptors respectively). Hypotensive agent that reduces p... |
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T21610 |
Bradykinin (acetate)
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Bradykinin Receptor
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Bradykinin (acetate) is an active peptide that is generated by the kallikrein-kinin system. It is a inflammatory mediator and also recognized as a neuromediator and regulator of several vascular and renal functions. Enzy... |
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TP1445 |
[Des-Arg9]-Bradykinin acetate
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Bradykinin Receptor
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T8809 |
[Des-Arg9]-Bradykinin TFA
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Bradykinin Receptor
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[Des-Arg9]-Bradykinin is an agonist of Bradykinin (B1) receptor that displays selectivity for B1 over B2 receptors. |
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TP1917L1 |
Sar-[D-Phe8]-des-Arg9-Bradykinin acetate
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Sar-[D-Phe8]-des-Arg9-Bradykinin acetate(126959-88-4 free base) |
Bradykinin Receptor
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Sar-[D-Phe8]-des-Arg9-Bradykinin acetate is a potent and selective bradykinin B1 receptor agonist (EC50 = 9.02 nM in rabbit aorta) that is resistant to aminopeptidase, kininase I and II (ACE) and neutral endopeptidase cl... |
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TP2268L |
Lys-Bradykinin acetate(342-10-9 free base)
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Bradykinin Receptor
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Lys-Bradykinin acetate is an endogenous bradykinin receptor agonist. |
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T7645 |
[Des-Arg9]-Bradykinin
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[Des-Arg9]-Bradykinin(2TFA) |
Bradykinin Receptor
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[Des-Arg9]-Bradykinin ([Des-Arg9]-Bradykinin(2TFA))(2TFA) is an agonist of Bradykinin (B1) receptor. |
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TP1210 |
Bradykinin (1-7)
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Bradykinin Fragment 1-7 |
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Bradykinin (1-7), an amino-truncated peptide derived from Bradykinin, is a metabolite formed through enzymatic cleavage by endopeptidase. |
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T36442 |
[Hyp3]-Bradykinin
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Bradykinin antagonist. |
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TP2268 |
Lys-Bradykinin
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Others
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Endogenous bradykinin receptor agonist |
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TP1747 |
Bradykinin (1-6)
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Bradykinin (1-6) is an amino-truncated Bradykinin peptide. Bradykinin (1-6) is a stable metabolite of Bradykinin, cleaved by carboxypeptidase Y (CPY).Bradykinin (1-6) is a fragment of bradykinin. Bradykinin activates pai... |
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TP1725 |
Bradykinin (1-5)
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Bradykinin (1-5) is a major stable metabolite of Bradykinin, formed by the proteolytic action of angiotensin-converting enzyme (ACE).The bradykinin (BK) fragment (1-5) (RPPGF) is among the most stable of naturally occurr... |
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TP1780 |
Bradykinin (1-3)
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Bradykinin (1-3) is a fragment of Bradykinin. Bradykinin is an activates pain receptors. |
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T25173 |
Bradykinin potentiator-5
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BPP-5a\,BPP 5a\,BPP5a\ |
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Bradykinin potentiator-5 is a peptide inflammatory mediator, causes blood vessels to dilate (enlarge), and therefore causes blood pressure to fall. |
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TP1918 |
Lys-[Des-Arg9]Bradykinin
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Endogenous potent and highly selective bradykinin B1 receptor agonist (Ki values are 0.12 and > 30000 nM at human B1 and B2 receptors respectively). Hypotensive agent that reduces peripheral vascular resistance in vivo. ... |
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TP2076 |
[Phe8Ψ(CH-NH)-Arg9]-Bradykinin
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Selective bradykinin B2 receptor agonist that is resistant to carboxypeptidase cleavage. 5-fold more potent and exhibits a more prolonged duration of action than bradykinin in vivo. |
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TP1917 |
Sar-[D-Phe8]-des-Arg9-Bradykinin
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Potent and selective bradykinin B1 receptor agonist (EC50 = 9.02 nM in rabbit aorta) that is resistant to aminopeptidase, kininase I and II (ACE) and neutral endopeptidase cleavage. Exhibits hypotensive and angiogenic ac... |
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T76385 |
[Tyr8] Bradykinin
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[Tyr8] Bradykinin, a B2 kinin receptor agonist, not only stimulates ERK1/2 phosphorylation but also serves as an internal standard [1]. |
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T76384 |
Methionyl-Lysyl-Bradykinin
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Methionyl-Lysyl-Bradykinin (Met-Lys-Bradykinin), a Bradykinin analogue, is a kinin [1] [2] . |
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T80979 |
T-kinin
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Ile-Ser-bradykinin |
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T-kinin (Ile-Ser-bradykinin) is a bradykinin-containing peptide utilized in inflammation research [1] [2]. |
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T76293 |
Lys-[Hyp3]-Bradykinin
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Lys-[Hyp3]-Bradykinin, a Bradykinin agonist and kinin, is a compound that can be extracted from human urine and is utilized in inflammation research [1]. |
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T76505 |
Bradykinin potentiator B
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Bradykinin Potentiator B (also known as Bradykinin Potentiating Peptide B), derived from the venom of Agkistrodon halys blomhoffi, serves as a potent ACE inhibitor. It effectively inhibits the activity of bradykinin inhi... |
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T76507 |
Bradykinin potentiator C
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Bradykinin Potentiator C, a potent inhibitor of angiotensin-converting enzyme (ACE) with an inhibitory concentration (IC 50) of 7.1 μM for rabbit lung ACE, is regarded as a prototype for functional peptides [1]. |
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T80117 |
Lys-(Des-Arg9,Leu8)-Bradykinin
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Bradykinin Receptor
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Lys-(Des-Arg9,Leu8)-Bradykinin is a selective antagonist of the bradykinin B1 receptor [1]. |
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T80072 |
Des-Arg9-[Leu8]-Bradykinin acetate
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Bradykinin Receptor
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Des-Arg9-[Leu8]-Bradykinin acetate is a potent antagonist of the bradykinin receptor 1 (B1R), utilized in renal fibrosis research [1]. |
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T73646 |
Lys-[Des-Arg9]Bradykinin TFA
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Lys-[Des-Arg9]Bradykinin TFA is a naturally occurring kinin that serves as a potent and highly selective agonist for the bradykinin B1 receptor, demonstrating binding affinities (K i values) of 0.12 nM, 1.7 nM, and 0.23 ... |
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T78435 |
Mca-(ala7,lys(dnp)9)-bradykinin
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Mca-(Ala7,Lys(Dnp)9)-bradykinin is a fluorogenic substrate that demonstrates high sensitivity for ECE-1 (endothelin-converting enzyme-1). It features a (7-methoxycoumarin-4-yl)acetyl (Mca) group for fluorescence and a 2,... |
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T5048 |
SSR240612
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Bradykinin Receptor
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SSR240612 is a potent, and orally active specific non-peptide bradykinin B1 receptor antagonist (Kis = 0.48-0.73 and 358-481 nM for B1 and B2 receptors, respectively). |
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T22344 |
Icatibant Acetate
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Bradykinin Receptor
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Icatibant Acetate, an antagonist of the bradykinin B2 receptor, is used in the treatment of hereditary angioedema. |
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T2086 |
ELN-441958
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ELN 441958 |
Bradykinin Receptor
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ELN-441958 is a potent, neutral antagonist of B1 receptor, inhibits the binding of the B1 agonist ligand [3H]DAKD to IMR-90 cells with Ki of 0.26 nM. ELN-441958(ELN 441958) is highly selective for B1 over B2 receptors. |
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T14358 |
Avoralstat
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BCX4161 |
Others
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Avoralstat (BCX4161) is an oral plasma kallikrein (PKK) inhibitor. Which is used for the treatment of hereditary angioedema. |
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T37795 |
Retrobradykinin
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Bradykinin analog nonapeptide. Reverse sequence of Bradykinin (Cat.No. 3004). Exhibits no significant kinin activity. Can be used as a negative control.
Lande (1962) Retrobradykinin: a peptide with the reverse sequence o... |
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TP1933 |
R715 TFA(185052-09-9 free base)
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R 715 |
Bradykinin Receptor
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R715 TFA(185052-09-9 free base) is a potent and selective bradykinin B1 receptor antagonist (pA2 = 8.49). Displays no activity at B2 receptors. Reduces mechanical hypernociception in a mouse model of neuropathic pain. Me... |
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T33421 |
MK-0686
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MK0686 |
Bradykinin Receptor
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MK-0686 is an orally available bradykinin B1 receptor antagonist with potential anti-inflammatory activity. |
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TP2075L |
Bombinakinin M acetate
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Bombinakinin M acetate(509151-65-9 free base) |
Bradykinin Receptor
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Bombinakinin M acetate is a potent bradykinin receptor agonist with high selectivity for mammalian arterial smooth muscle bradykinin receptors and is approximately 50 times more potent than bradykinin. |
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T21060L |
NPC 567 acetate
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NPC 567 acetate(109333-26-8 Free base) |
Bradykinin Receptor
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NPC 567 acetate is a bradykinin B2 antagonist and can be used in studies about the treatment of allergic airway disease. |
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T34485 |
Safotibant
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LF220542,LF 220542,LF 22-0542,LF-220542,LF-22-0542,LF22-0542 |
Bradykinin Receptor
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Safotibant (LF-22-0542) is a bradykinin B1 receptor antagonist with anti-inflammatory and analgesic activity for the topical treatment of diabetic macular edema. |
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T26627L |
Anatibant 2HCl
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Anatibant 2HCl(209733-45-9 Free base) |
Bradykinin Receptor
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Anatibant 2HCl is a small molecule bradykinin B2 receptor antagonist for the treatment of neurological disorders and may be used in the study of brain injury. |
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T24799 |
SKA-111
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SKA 111,SKA111 |
Potassium Channel
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SKA-111 is a selective calcium-activated potassium phannel (potassium phannel ) KCa3.1 activator that induces membrane hyperpolarization in porcine endothelial cells.SKA-111 binds to the interface between the CaM N-valve... |
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T4200 |
Sacubitril hemicalcium salt
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AHU-377 (hemicalcium salt),AHU377 calcium salt |
Neprilysin
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Sacubitril hemicalcium salt (AHU377 calcium salt) is a potent NEP inhibitor with an IC50 of 5 nM. Sacubitril hemicalcium salt is a component of the heart failure medicine LCZ696. Sacubitril hemicalcium salt is a prodrug ... |
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TP1931L1 |
[D-Arg1,D-Phe5,D-Trp7,9,Leu11]-Substance P acetate
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[D-Arg1,D-Phe5,D-Trp7,9,Leu11]-Substance P acetate(96736-12-8 free base) |
cholecystokinin
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[D-Arg1,D-Phe5,D-Trp7,9,Leu11]-Substance P acetate ([D-Arg1,D-Phe5,D-Trp7,9,Leu11]-Substance P acetate (96736-12-8 free base)) is a broad spectrum neuropeptide inverse agonist and antagonist. Potent full inverse agonist ... |
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T15347 |
FR167344 free base
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Others
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FR167344 free base is an orally active and nonpeptide antagonist of bradykinin receptor B2. FR167344 free base displays a high-affinity binding to the B2 receptor (IC50: 65 nM). It has no binding affinity for the B1 rece... |
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T21060 |
NPC 567
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NPC 567 is an antagonist of the bradykinin receptor. |
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T27377 |
FR190997
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FR-190997,FR 190997 |
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FR190997 is an agonist of bradykinin B2 receptor. |
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T70750 |
Deltibant
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Deltibantis a bradykinin receptor antagonist. |
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T70574 |
NPC 17761
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NPC 17761 is a bradykinin receptor antagonist. |
